Nanomedicines have significant potential for cancer treatment. Although the majority of
nanomedicines currently tested in clinical trials utilize simple, biocompatible liposome …

Nearly all deaths caused by solid cancers occur as a result of metastasis—the formation of
secondary tumours in distant organs such as the lungs, liver, brain and bone. A major …

The surface of a cell represents a collection of macromolecules, which provides the cell with
a unique cellular landscape specific to the type and state of the cell. Ligands that …

The signaling network downstream of the ErbB family of receptors has been extensively
targeted by cancer therapeutics; however, understanding the relative importance of the …

Recognition of molecular diversity of cell surface proteomes in disease is essential for the
development of targeted therapies. Progress in targeted therapeutics requires establishing …

Several monoclonal antibodies that target cell surface receptors have gained approval by
the US Food and Drug Administration and are widely used in the treatment of some cancers …

New peptide-based probes to facilitate the molecular imaging of disease are rapidly
evolving due to implementation of combinatorial chemistry and bacteriophage (phage) …

Adipose stromal cells (ASCs) serve as mesenchymal progenitors in white adipose tissue
(WAT). Intercellular interactions involving ASCs have remained obscure. By merging phage …

Nanostructured scaffolds recently showed great promise in tissue engineering:
nanomaterials can be tailored at the molecular level and scaffold morphology may more …

Molecular imaging has rapidly emerged as a discipline with the potential to impact
fundamental biomedical research and clinical practice. Within this field, optical imaging …