Aided by genome-mining strategies, knowledge of the prevalence and diversity of
ribosomally synthesized natural products (RNPs) is rapidly increasing. Among these are the …

The increasing number of multidrug-resistant pathogens, along with the small number of
new antimicrobials under development, leads to an increased need for novel alternatives …

Background Ribosomally synthesized and post-translationally modified peptides (RiPPs)
are a diverse group of biologically active bacterial molecules. Due to the conserved genomic …

Bacteriocins, a heterogenous group of antibacterial ribosomally synthesized peptides, have
potential as bio-preservatives in in a wide range of foods and as future therapeutics for the …

Ribosomally synthesized and post-translationally modified peptides, or RiPPs, which have
mainly isolated from microbes as well as plants and animals, are an ever-expanding group …

Bacteria produce under certain stress conditions bacteriocins and microcins that display
antibacterial activity against closely related species for survival. Bacteriocins and microcins …

Bacillus licheniformis is a well-known probiotic that can be found in a variety of foods. The
strain Bacillus licheniformis MCC 2514 was previously characterized by our group for its bio …

The structural complexity of nonribosomal peptides (NRPs) impeding economic chemical
synthesis and poor cultivability of source organisms limits the development of bioprocesses …

Bacteriocins are a diverse group of ribosomally synthesised antimicrobial peptides/proteins
that play an important role in self-defence. They are widely used as bio-preservatives and …

Gram-negative bacteria provide a particular challenge to antibacterial drug discovery due to
their cell envelope structure. Compound entry is impeded by the lipopolysaccharide (LPS) of …