[HTML][HTML] Comparative systematic review and meta-analysis of reactogenicity, immunogenicity and efficacy of vaccines against SARS-CoV-2

I McDonald, SM Murray, CJ Reynolds, DM Altmann… - npj Vaccines, 2021 - nature.com
As SARS-CoV-2 vaccines are deployed worldwide, a comparative evaluation is important to
underpin decision-making. We here report a systematic literature review and meta-analysis …

[HTML][HTML] COVID-19: Mechanisms of vaccination and immunity

DE Speiser, MF Bachmann - Vaccines, 2020 - mdpi.com
Vaccines are needed to protect from SARS-CoV-2, the virus causing COVID-19. Vaccines
that induce large quantities of high affinity virus-neutralizing antibodies may optimally …

[HTML][HTML] Status report on COVID-19 vaccines development

A Kumar, WE Dowling, RG Román… - Current Infectious …, 2021 - Springer
Abstract Purpose of Review The emergence of the severe acute respiratory syndrome
coronavirus-2 (SARS-CoV-2) has affected lives of billions of individuals, globally. There is …

[HTML][HTML] Viral emerging diseases: challenges in developing vaccination strategies

M Trovato, R Sartorius, L D'Apice, R Manco… - Frontiers in …, 2020 - frontiersin.org
In the last decades, a number of infectious viruses have emerged from wildlife or re-
emerged, generating serious threats to the global health and to the economy worldwide …

COVID-19 vaccine candidates based on modified vaccinia virus Ankara expressing the SARS-CoV-2 spike protein induce robust T-and B-cell immune responses and …

J García-Arriaza, U Garaigorta, P Pérez… - Journal of …, 2021 - Am Soc Microbiol
Vaccines against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the
causative agent of the coronavirus disease 2019 (COVID-19) pandemic, are urgently …

Potential adjuvants for the development of a SARS-CoV-2 vaccine based on experimental results from similar coronaviruses

T Gupta, SK Gupta - International immunopharmacology, 2020 - Elsevier
The extensive efforts around the globe are being made to develop a suitable vaccine
against COVID-19 (Coronavirus Disease-19) caused by SARS-CoV-2 (Severe Acute …

COVID-19 vaccines:“Warp Speed” needs mind melds, not warped minds

JP Moore, PJ Klasse - Journal of virology, 2020 - Am Soc Microbiol
In this review, we address issues that relate to the rapid “Warp Speed” development of
vaccines to counter the COVID-19 pandemic. We review the antibody response that is …

[HTML][HTML] Safety, tolerability, and immunogenicity of COVID-19 vaccines: a systematic review and meta-analysis

P Yuan, P Ai, Y Liu, Z Ai, Y Wang, W Cao, X Xia… - MedRxiv, 2020 - ncbi.nlm.nih.gov
We aimed to summarize reliable medical evidence by the meta-analysis of all published
clinical trials that investigated the safety, tolerability, and immunogenicity of vaccine …

[PDF][PDF] SARS-CoV-2 protein subunit vaccination of mice and rhesus macaques elicits potent and durable neutralizing antibody responses

M Mandolesi, DJ Sheward, L Hanke, J Ma… - Cell Reports …, 2021 - cell.com
The outbreak and spread of SARS-CoV-2 (severe acute respiratory syndrome-coronavirus-
2) is a current global health emergency, and effective prophylactic vaccines are needed …

[HTML][HTML] Design of a highly thermotolerant, immunogenic SARS-CoV-2 spike fragment

SK Malladi, R Singh, S Pandey, S Gayathri… - Journal of Biological …, 2021 - ASBMB
Virtually all SARS-CoV-2 vaccines currently in clinical testing are stored in a refrigerated or
frozen state prior to use. This is a major impediment to deployment in resource-poor settings …