Biomedical applications of hydrogels in drug delivery system: An update

P Kesharwani, A Bisht, A Alexander, V Dave… - Journal of Drug Delivery …, 2021 - Elsevier
Conventional drug delivery system generally deals with the issues involving repeated
dosing and systemic toxicities. Since few decades, hydrogels have played a significant role …

Chitosan: an update on potential biomedical and pharmaceutical applications

RCF Cheung, TB Ng, JH Wong, WY Chan - Marine drugs, 2015 - mdpi.com
Chitosan is a natural polycationic linear polysaccharide derived from chitin. The low
solubility of chitosan in neutral and alkaline solution limits its application. Nevertheless …

Micro‐nanocarriers based drug delivery technology for blood‐brain barrier crossing and brain tumor targeting therapy

L Wang, Y Shi, J Jiang, C Li, H Zhang, X Zhang… - Small, 2022 - Wiley Online Library
The greatest obstacle to using drugs to treat brain tumors is the blood‐brain barrier (BBB),
making it difficult for conventional drug molecules to enter the brain. Therefore, how to safely …

Injectable hydrogels for localized cancer therapy

D Fan, Y Tian, Z Liu - Frontiers in chemistry, 2019 - frontiersin.org
Traditional intravenous chemotherapy is relative to many systemic side effects, including
myelosuppression, liver or kidney dysfunction, and neurotoxicity. As an alternative method …

Indocyanine green delivery systems for tumour detection and treatments

EP Porcu, A Salis, E Gavini, G Rassu, M Maestri… - Biotechnology …, 2016 - Elsevier
Indocyanine green (ICG) is a cyanine compound that displays fluorescent properties in the
near infrared region. This dye is employed for numerous indications but nowadays its major …

Composite chitosan/alginate hydrogel for controlled release of deferoxamine: A system to potentially treat iron dysregulation diseases

G Rassu, A Salis, EP Porcu, P Giunchedi, M Roldo… - Carbohydrate …, 2016 - Elsevier
Recently, the potential application of deferoxamine (DFO) in several iron dysregulation
diseases has been highlighted. However, DFO presents significant limitations in clinical use …

Biocompatible chitosan based hydrogels for potential application in local tumour therapy

AM Olaru, L Marin, S Morariu, G Pricope… - Carbohydrate …, 2018 - Elsevier
A series of hydrogels based on chitosan polyamine and nitrosalicylaldehyde were prepared
via dynamic covalent chemistry (DCC), by imination and transimination reactions towards …

Chitosan nanoparticles for therapy and theranostics of hepatocellular carcinoma (HCC) and liver-targeting

MC Bonferoni, E Gavini, G Rassu, M Maestri… - Nanomaterials, 2020 - mdpi.com
Chitosan nanoparticles are well-known delivery systems widely used as polymeric carriers
in the field of nanomedicine. Chitosan is a carbohydrate of natural origin: it is a …

Aquaculture and its by-products as a source of nutrients and bioactive compounds

F Al Khawli, FJ Martí-Quijal, E Ferrer, MJ Ruiz… - Advances in food and …, 2020 - Elsevier
Underutilized marine resources (eg, algae, fish, and shellfish processing by-products), as
sustainable alternatives to livestock protein and interesting sources of bioactive compounds …

Advancements in the development on new liquid embolic agents for use in therapeutic embolisation

J Lord, H Britton, SG Spain, AL Lewis - Journal of Materials Chemistry …, 2020 - pubs.rsc.org
Liquid formulations have a well-established role in therapeutic embolisation of blood
vessels with the widespread use of cyanoacrylate glues, precipitating polymer suspensions …