A review of current trends with type 2 diabetes epidemiology, aetiology, pathogenesis, treatments and future perspectives

J Reed, S Bain, V Kanamarlapudi - Diabetes, Metabolic Syndrome …, 2021 - Taylor & Francis
Abstract Type 2 diabetes (T2D), which has currently become a global pandemic, is a
metabolic disease largely characterised by impaired insulin secretion and action. Significant …

Role of polyphenols in combating Type 2 Diabetes and insulin resistance

M Shahwan, F Alhumaydhi, GM Ashraf… - International journal of …, 2022 - Elsevier
Compromised carbohydrate metabolism leading to hyperglycemia is the primary metabolic
disorder of non-insulin-dependent diabetes mellitus. Reformed digestion and altered …

Type 1 diabetes

LA DiMeglio, C Evans-Molina, RA Oram - The Lancet, 2018 - thelancet.com
Type 1 diabetes is a chronic autoimmune disease characterised by insulin deficiency and
resultant hyperglycaemia. Knowledge of type 1 diabetes has rapidly increased over the past …

Methylglyoxal, a highly reactive dicarbonyl compound, in diabetes, its vascular complications, and other age-related diseases

CG Schalkwijk, CDA Stehouwer - Physiological reviews, 2020 - journals.physiology.org
The formation and accumulation of methylglyoxal (MGO), a highly reactive dicarbonyl
compound, has been implicated in the pathogenesis of type 2 diabetes, vascular …

Type 1 diabetes in 2017: global estimates of incident and prevalent cases in children and adults

A Green, SM Hede, CC Patterson, SH Wild… - Diabetologia, 2021 - Springer
Aims/hypothesis Data on type 1 diabetes incidence and prevalence are limited, particularly
for adults. This study aims to estimate global numbers of incident and prevalent cases of …

The global epidemiology of diabetes and kidney disease

DN Koye, DJ Magliano, RG Nelson… - Advances in chronic kidney …, 2018 - Elsevier
The prevalence of diabetes is increasing worldwide, with the greatest increases occurring in
low-and middle-income countries. In most developed countries, type 2 diabetes is presently …

Differentiation of diabetes by pathophysiology, natural history, and prognosis

JS Skyler, GL Bakris, E Bonifacio, T Darsow… - Diabetes, 2017 - Am Diabetes Assoc
The American Diabetes Association, JDRF, the European Association for the Study of
Diabetes, and the American Association of Clinical Endocrinologists convened a research …

Obstructive sleep apnea and diabetes: a state of the art review

S Reutrakul, B Mokhlesi - Chest, 2017 - Elsevier
OSA is a chronic treatable sleep disorder and a frequent comorbidity in patients with type 2
diabetes. Cardinal features of OSA, including intermittent hypoxemia and sleep …

[HTML][HTML] Diabetes mellitus: The epidemic of the century

AT Kharroubi, HM Darwish - World journal of diabetes, 2015 - ncbi.nlm.nih.gov
The epidemic nature of diabetes mellitus in different regions is reviewed. The Middle East
and North Africa region has the highest prevalence of diabetes in adults (10.9%) whereas …

[HTML][HTML] Frequency and phenotype of type 1 diabetes in the first six decades of life: a cross-sectional, genetically stratified survival analysis from UK Biobank

NJ Thomas, SE Jones, MN Weedon… - The Lancet Diabetes & …, 2018 - thelancet.com
Background Type 1 diabetes is typically considered a disease of children and young adults.
Genetic susceptibility to young-onset type 1 diabetes is well defined and does not …