Sialic acids are terminal acidic monosaccharides, which influence the chemical and
biological features of glycoconjugates. Their removal catalyzed by a sialidase modulates …

A bstract This review summarizes the recent research development on vertebrate sialidase
biology. Sialic acid-containing compounds play important roles in many physiological …

Dengue is the most prevalent arboviral disease in humans and a major public health
problem worldwide. Systemic plasma leakage, leading to hypovolemic shock and potentially …

Human adenovirus species D (HAdV-D) types are currently being explored as vaccine
vectors for coronavirus disease 2019 (COVID-19) and other severe infectious diseases. The …

Sialic acids are important molecule with high structural diversity. They are known to occur in
higher animals such as Echinoderms, Hemichordata, Cephalochorda, and Vertebrata and …

Cancer is a major cause of death in both developing and developed countries. Early
detection and efficient therapy can greatly enhance survival. Aberrant glycosylation has …

Covering: 2000 to 2011 The imminent threat of influenza pandemics and repeatedly
reported emergence of new drug-resistant influenza virus strains demonstrate the urgent …

Anew strain of influenza A virus (novel in-fluenza A H1N1) that originated in swine has rapid
ly spread from the initial outbreak in Mexico and the southern United States to Canada and …

Sialidases, or neuraminidases, are enzymes that catalyze the hydrolysis of sialic acid (Sia)-
containing molecules, mostly removal of the terminal Sia (desialylation). By desialylation …

The composition and functions of the secreted proteome are controlled by the life spans of
different proteins. However, unlike intracellular protein fate, intrinsic factors determining …