The immune response to influenza in older humans: beyond immune senescence

JE McElhaney, CP Verschoor, MK Andrew, L Haynes… - Immunity & …, 2020 - Springer
Despite widespread influenza vaccination programs, influenza remains a major cause of
morbidity and mortality in older adults. Age-related changes in multiple aspects of the …

More than just gene therapy vectors: Lentiviral vector pseudotypes for serological investigation

K Toon, EM Bentley, G Mattiuzzo - Viruses, 2021 - mdpi.com
Serological assays detecting neutralising antibodies are important for determining the
immune responses following infection or vaccination and are also often considered a …

COVID-19 in Colombia endpoints. Are we different, like Europe?

P Amariles, J Granados, M Ceballos… - Research in Social and …, 2021 - Elsevier
The infection by the new coronavirus (SARS-CoV-2) has taken the dimension of a
pandemic, affecting more than 160 countries in a few weeks. In Colombia, despite the …

Bivalent H1 and H3 COBRA recombinant hemagglutinin vaccines elicit seroprotective antibodies against H1N1 and H3N2 influenza viruses from 2009 to 2019

JD Allen, TM Ross - Journal of Virology, 2022 - Am Soc Microbiol
Commercial influenza virus vaccines often elicit strain-specific immune responses and have
difficulties preventing illness caused by antigenically drifted viral variants. In the last 20 …

A single-shot vaccine approach for the universal influenza A vaccine candidate M2e

R Kavishna, TY Kang, M Vacca… - Proceedings of the …, 2022 - National Acad Sciences
Influenza, commonly referred to as “flu,” is a major global public health concern and a huge
economic burden to societies. Current influenza vaccines need to be updated annually to …

[HTML][HTML] Intradermal administration of influenza vaccine with trehalose and pullulan-based dissolving microneedle arrays

Y Tian, J Lee, K van der Maaden, Y Bhide… - Journal of …, 2022 - Elsevier
Most influenza vaccines are administered via intramuscular injection which has several
disadvantages that might jeopardize the compliance of vaccinees. Intradermal …

Repeated exposure to heterologous hepatitis C viruses associates with enhanced neutralizing antibody breadth and potency

N Frumento, A Figueroa, T Wang… - The Journal of …, 2022 - Am Soc Clin Investig
A prophylactic hepatitis C virus (HCV) vaccine that elicits neutralizing antibodies could be
key to HCV eradication. However, the genetic and antigenic properties of HCV envelope …

Prolonging the delivery of influenza virus vaccine improves the quantity and quality of the induced immune responses in mice

M Beukema, S Gong, K Al-Jaawni… - Frontiers in …, 2023 - frontiersin.org
Introduction Influenza vaccines play a vital role in protecting individuals from influenza virus
infection and severe illness. However, current influenza vaccines have suboptimal efficacy …

Heterologous immune responses of serum IgG and secretory IgA against the spike protein of endemic coronaviruses during severe COVID-19

WL Smit, S van Tol, S Wal, F van Vulpen… - Frontiers in …, 2022 - frontiersin.org
Defining immune correlates of disease severity is important to better understand the
immunopathogenesis in COVID-19. Here we made use of a protein microarray platform to …

Adeno‐associated virus‐vectored influenza vaccine elicits neutralizing and Fcγ receptor‐activating antibodies

DE Demminger, L Walz, K Dietert… - EMBO molecular …, 2020 - embopress.org
The current seasonal inactivated influenza vaccine protects only against a narrow range of
virus strains as it triggers a dominant antibody response toward the hypervariable …