Pharmacological attributes of Bacopa monnieri extract: Current updates and clinical manifestation

U Fatima, S Roy, S Ahmad, S Ali, WM Elkady… - Frontiers in …, 2022 - frontiersin.org
Bacopa monnieri has been used for centuries in Ayurvedic medicine, alone or in
combination with other herbs, as a memory and learning enhancer, sedative, and anti …

[HTML][HTML] Exploration of therapeutic applicability and different signaling mechanism of various phytopharmacological agents for treatment of breast cancer

V Singh, K Kumar, D Purohit, R Verma… - Biomedicine & …, 2021 - Elsevier
Background Cancer is one of the most dreaded diseases characterized by uncontrolled
proliferation of abnormal cells that occurs due to impairment of cell division and apoptosis …

[HTML][HTML] Investigating neuroprotective roles of Bacopa monnieri extracts: Mechanistic insights and therapeutic implications

U Fatima, S Roy, S Ahmad, LA Al-Keridis… - Biomedicine & …, 2022 - Elsevier
Bacopa monnieri (Brahmi) is a well-known perennial, creeping herb of the Indian Ayurveda
system; it contains numerous bioactive phytoconstituents implicated in the therapeutic …

Investigating the Neuroprotective and Cognitive-Enhancing Effects of Bacopa monnieri: A Systematic Review Focused on Inflammation, Oxidative Stress …

LJ Valotto Neto, M Reverete de Araujo… - Antioxidants, 2024 - mdpi.com
The aging of the global population has increased the prevalence of neurodegenerative
conditions. Bacopa monnieri (BM), an herb with active compounds, such as bacosides A …

Investigating MARK4 inhibitory potential of Bacopaside II: targeting Alzheimer's disease

S Anwar, T Mohammad, MK Azhar, H Fatima… - International journal of …, 2023 - Elsevier
Microtubule affinity regulating kinase 4 (MARK4) is known to hyperphosphorylate tau
protein, which subsequently causes Alzheimer's disease (AD). MARK4 is a well-validated …

Phytochemicals bridging autophagy induction and alpha-synuclein degradation in parkinsonism

F Limanaqi, F Biagioni, CL Busceti, L Ryskalin… - International journal of …, 2019 - mdpi.com
Among nutraceuticals, phytochemical-rich compounds represent a source of naturally-
derived bioactive principles, which are extensively studied for potential beneficial effects in a …

CD47-mediated DTIC-loaded chitosan oligosaccharide-grafted nGO for synergistic chemo-photothermal therapy against malignant melanoma

X Zhan, W Teng, K Sun, J He, J Yang, J Tian… - Materials Science and …, 2021 - Elsevier
Abstract Nano-graphene oxide (nGO), an effective drug nanocarrier, is used for
simultaneous photothermal therapy (PTT) and near-infrared fluorescence imaging …

Isobavachalcone isolated from Psoralea corylifolia inhibits cell proliferation and induces apoptosis via inhibiting the AKT/GSK-3β/β-catenin pathway in colorectal …

Y Li, X Qin, P Li, H Zhang, T Lin, Z Miao… - Drug design …, 2019 - Taylor & Francis
Background: Colorectal cancer (CRC) is a common form of cancer associated with a high
mortality rate and poor prognosis. Given the limited efficacy of current therapies for CRC …

Combined pharmacological administration of AQP1 ion channel blocker AqB011 and water channel blocker Bacopaside II amplifies inhibition of colon cancer cell …

ML De Ieso, JV Pei, S Nourmohammadi, E Smith… - Scientific reports, 2019 - nature.com
Abstract Aquaporin-1 (AQP1) has been proposed as a dual water and cation channel that
when upregulated in cancers enhances cell migration rates; however, the mechanism …

Bacopasides I and II act in synergy to inhibit the growth, migration and invasion of breast cancer cell lines

HM Palethorpe, E Smith, Y Tomita, M Nakhjavani… - Molecules, 2019 - mdpi.com
Bacopaside (bac) I and II are triterpene saponins purified from the medicinal herb Bacopa
monnieri. Previously, we showed that bac II reduced endothelial cell migration and tube …