[HTML][HTML] Malaria: biology and disease

AF Cowman, J Healer, D Marapana, K Marsh - Cell, 2016 - cell.com
Malaria has been a major global health problem of humans through history and is a leading
cause of death and disease across many tropical and subtropical countries. Over the last …

Merozoite surface proteins in red blood cell invasion, immunity and vaccines against malaria

JG Beeson, DR Drew, MJ Boyle, G Feng… - FEMS microbiology …, 2016 - academic.oup.com
Malaria accounts for an enormous burden of disease globally, with Plasmodium falciparum
accounting for the majority of malaria, and P. vivax being a second important cause …

[HTML][HTML] PCRCR complex is essential for invasion of human erythrocytes by Plasmodium falciparum

SW Scally, T Triglia, C Evelyn, BA Seager… - Nature …, 2022 - nature.com
The most severe form of malaria is caused by Plasmodium falciparum. These parasites
invade human erythrocytes, and an essential step in this process involves the ligand PfRh5 …

Malaria biology and disease pathogenesis: insights for new treatments

LH Miller, HC Ackerman, X Su, TE Wellems - Nature medicine, 2013 - nature.com
Plasmodium falciparum malaria, an infectious disease caused by a parasitic protozoan,
claims the lives of nearly a million children each year in Africa alone and is a top public …

Basigin is a receptor essential for erythrocyte invasion by Plasmodium falciparum

C Crosnier, LY Bustamante, SJ Bartholdson, AK Bei… - Nature, 2011 - nature.com
Erythrocyte invasion by Plasmodium falciparum is central to the pathogenesis of malaria.
Invasion requires a series of extracellular recognition events between erythrocyte receptors …

[HTML][HTML] Revealing the Sequence and Resulting Cellular Morphology of Receptor-Ligand Interactions during Plasmodium falciparum Invasion of Erythrocytes

GE Weiss, PR Gilson, T Taechalertpaisarn… - PLoS …, 2015 - journals.plos.org
During blood stage Plasmodium falciparum infection, merozoites invade uninfected
erythrocytes via a complex, multistep process involving a series of distinct receptor-ligand …

The cellular and molecular basis for malaria parasite invasion of the human red blood cell

AF Cowman, D Berry, J Baum - Journal of cell Biology, 2012 - rupress.org
Malaria is a major disease of humans caused by protozoan parasites from the genus
Plasmodium. It has a complex life cycle; however, asexual parasite infection within the blood …

Malaria immunity in man and mosquito: insights into unsolved mysteries of a deadly infectious disease

PD Crompton, J Moebius, S Portugal… - Annual review of …, 2014 - annualreviews.org
Malaria is a mosquito-borne disease caused by parasites of the obligate intracellular
Apicomplexa phylum the most deadly of which, Plasmodium falciparum, prevails in Africa …

[HTML][HTML] Essential role of the PfRh5/PfRipr/CyRPA complex during Plasmodium falciparum invasion of erythrocytes

JC Volz, A Yap, X Sisquella, JK Thompson, NTY Lim… - Cell host & …, 2016 - cell.com
Plasmodium falciparum parasites in the merozoite stage invade human erythrocytes and
cause malaria. Invasion requires multiple interactions between merozoite ligands and …

A newly discovered protein export machine in malaria parasites

TF de Koning-Ward, PR Gilson, JA Boddey, M Rug… - Nature, 2009 - nature.com
Several hundred malaria parasite proteins are exported beyond an encasing vacuole and
into the cytosol of the host erythrocyte, a process that is central to the virulence and viability …