Oxidative stress, through the production of reactive oxygen species, is a natural
consequence of aerobic metabolism. Escherichia coli has several major regulators activated …

For many bacteria, successful growth and survival depends on efficient adaptation to rapidly
changing conditions. In Escherichia coli, the RpoS alternative sigma factor plays a central …

Bacterial small RNAs (sRNAs) have been implicated in various aspects of post-
transcriptional gene regulation. Here, we demonstrate that sRNAs also act at the level of …

There is an urgent need for new, effective agents in topical wound care, and selected
honeys show potential in this regard. Using a medical-grade honey, eight species of …

Background Glycerol has enhanced its biotechnological importance since it is a byproduct of
biodiesel synthesis. A study of Escherichia coli physiology during growth on glycerol was …

Understanding mechanisms of bacterial pathogenesis is critical for infectious disease
control and treatment. Infection is a sophisticated process that requires the participation of …

Identifying the factors that determine microbial growth rate under various environmental and
genetic conditions is a major challenge of systems biology. While current genome-scale …

Bacterial cells often face hostile environmental conditions, to which they adapt by activation
of stress responses. In E scherichia coli, environmental stresses resulting in significant …

The general stress response (GSR) is a widespread strategy developed by bacteria to adapt
and respond to their changing environments. The GSR is induced by one or multiple …

Honey has been valued as a powerful antimicrobial since ancient times. However, the
understanding of the underlying antibacterial mechanism is incomplete. The complexity and …