Importance After initial resuscitation, critically ill children may accumulate fluid and develop
fluid overload. Accruing evidence suggests that fluid overload contributes to greater …

Objectives To develop evidence-based recommendations for clinicians caring for children
(including infants, school-aged children, and adolescents) with septic shock and other …

Objectives: To assess the validity of Vasoactive-Inotropic Score as a scoring system for
cardiovascular support and surrogate outcome in pediatric sepsis. Design: Secondary …

Objectives: We examined the association between fluid overload and major adverse kidney
events in critically ill patients requiring continuous renal replacement therapy for acute …

The use of kidney support therapy (KST) for use in managing patients with acute kidney
injury (AKI) has expanded greatly in the last several decades. The growing use of KST …

Rationale: Acute kidney injury (AKI), a common complication of sepsis, is associated with
substantial morbidity and mortality and lacks definitive disease-modifying therapy. Early …

Objectives: To analyze the epidemiology of pediatric acute kidney injury requiring
continuous renal replacement therapy and identify prognostic factors affecting mortality …

OBJECTIVES: To evaluate the use of direct hemoperfusion with polymyxin B-immobilized
fiber (PMX-DHP) as adjunctive therapy during pediatric patients with septic shock. DESIGN …

目的探讨早期连续性血液净化(CBP) 治疗对严重脓毒症患者的器官保护作用和应用时机选择.
方法采用双盲随机对照研究方法, 选择2013 年1 月至2015 年1 月武汉市第一医院重症医学科 …

Acute kidney injury (AKI), a common complication in paediatric intensive care units (PICU),
is associated with increased morbidity and mortality. In this single centre, prospective …