[HTML][HTML] Endpoints for clinical trials in ophthalmology

L Schmetterer, H Scholl, G Garhöfer… - Progress in Retinal and …, 2023 - Elsevier
With the identification of novel targets, the number of interventional clinical trials in
ophthalmology has increased. Visual acuity has for a long time been considered the gold …

Primary glaucomas in adults: Epidemiology and public health‐A review

TF Reis, JS Paula, JM Furtado - Clinical & experimental …, 2022 - Wiley Online Library
Glaucoma is a mixed group of optic neuropathies that lead to irreversible visual field loss
and blindness if left untreated. It is estimated that 3.5% of the global population aged 40 to …

[HTML][HTML] Co-occurrence of chronic kidney disease and glaucoma: epidemiology and etiological mechanisms

W Liu, R Guo, D Huang, J Ji, RT Gansevoort… - survey of …, 2023 - Elsevier
As the histology, physiology, and pathophysiology of eyes and kidneys show substantial
overlap, it has been suggested that eye and kidney diseases, such as glaucoma and chronic …

Effect of antihypertensive medications on the risk of open-angle glaucoma

JS Lee, HR Cha, HW Bae, SY Lee, W Choi, SW Lee… - Scientific reports, 2023 - nature.com
The purpose of this study was to identify the effect of antihypertensive medication on risks of
open-angle glaucoma (OAG) among patients diagnosed with hypertension (HTN). A total of …

[HTML][HTML] Blood pressure measures and incident primary open-angle glaucoma

C Macri, CX Wong, SJ Tu, R Casson… - … & Visual Science, 2022 - tvst.arvojournals.org
Purpose: To investigate the association of systemic blood pressure and incident primary
open-angle glaucoma (POAG) using a large open-access database. Methods: Prospective …

Advancing glaucoma care: integrating artificial intelligence in diagnosis, management, and progression detection

Y Zhu, R Salowe, C Chow, S Li, O Bastani, JM O'Brien - Bioengineering, 2024 - mdpi.com
Glaucoma, the leading cause of irreversible blindness worldwide, comprises a group of
progressive optic neuropathies requiring early detection and lifelong treatment to preserve …

The relevance of arterial blood pressure in the management of glaucoma progression: a systematic review

J Van Eijgen, JD Melgarejo… - American Journal of …, 2024 - academic.oup.com
BACKGROUND Glaucoma is one of the leading causes of global blindness and is expected
to co-occur more frequently with vascular morbidities in the upcoming years, as both are …

[HTML][HTML] Effect of 24-h blood pressure dysregulations and reduced ocular perfusion pressure in open-angle glaucoma progression

JD Melgarejo, JV Eijgen, D Wei, GE Maestre… - Journal of …, 2023 - journals.lww.com
Background: Low ocular perfusion pressure (OPP), which depends on the mean arterial
pressure (MAP) and intraocular pressure (IOP), is associated with glaucoma. We studied 24 …

Systematic review and appraisal of quality, definitions and treatment recommendations of clinical guidelines for glaucoma suspects

Z Wu, S Karunaratne, GS Ang… - Clinical & …, 2024 - Wiley Online Library
Background To appraise the quality of clinical practice guidelines for glaucoma suspects,
and to assess their consistency for how a 'glaucoma suspect'is defined and their …

Association of blood pressure with rates of macular ganglion cell complex thinning in patients with glaucoma

V Mohammadzadeh, E Su, M Mohammadi… - JAMA …, 2023 - jamanetwork.com
Importance There are scarce data on the association of blood pressure measures with
subsequent macular structural rates of change in patients with glaucoma. Objective To …