Retinoic acid and arsenic trioxide induce lasting differentiation and demethylation of target genes in APL cells
Acute promyelocytic leukemia (APL) is characterized by arrested differentiation of
promyelocytes. Patients treated with all-trans retinoic acid (ATRA) alone experience relapse …
promyelocytes. Patients treated with all-trans retinoic acid (ATRA) alone experience relapse …
Post-translational modification of retinoic acid receptor alpha and its roles in tumor cell differentiation
A Xu, N Zhang, J Cao, H Zhu, B Yang, Q He… - Biochemical …, 2020 - Elsevier
Retinoic acid (RA) is a well-known differentiation inducer that exerts its effects by binding to
nuclear RA receptors. Retinoic acid receptor α (RARα), as an important nuclear RA receptor …
nuclear RA receptors. Retinoic acid receptor α (RARα), as an important nuclear RA receptor …
All-trans retinoic acid, arsenic trioxide, and anthracycline-based chemotherapy improves outcome in newly diagnosed acute promyelocytic leukemia regardless of …
L Xu, Y Su, H Tao - Current Medical Science, 2021 - Springer
All-trans retinoic acid (ATRA) and pre-upfront arsenic trioxide (ATO) have revolutionized the
therapy of acute promyelocytic leukemia (APL). However, internal tandem duplication of …
therapy of acute promyelocytic leukemia (APL). However, internal tandem duplication of …
Avaliação de protocolo quimioterápico para tratamento de leucemia promielocítica aguda na infância e adolescência
CNM Breviglieri - 2022 - teses.usp.br
Objetivo: Avaliar os resultados de sobrevida global e sobrevida livre de eventos das
crianças e adolescentes tratados por protocolo de tratamento da leucemia promielocítica …
crianças e adolescentes tratados por protocolo de tratamento da leucemia promielocítica …
Induktion von Apoptose durch Arsentrioxid und Antimontrioxid in hämatologischen Neoplasien-von den Grundlagen bis zur klinischen Anwendung
S Susan - 2024 - oparu.uni-ulm.de
Es ist bekannt, dass Arsen-und Antimontrioxid (As2O3, Sb2O3) in einer Vielzahl von
Leukämie-und Lymphomzelllinien Apoptose auszulösen vermag. Dabei benötigt man …
Leukämie-und Lymphomzelllinien Apoptose auszulösen vermag. Dabei benötigt man …
[PDF][PDF] Induktion von Apoptose durch Arsentrioxid und Antimontrioxid in hämatologischen Neoplasien-von den Grundlagen bis zur klinischen Anwendung
H Schrezenmeier - oparu.uni-ulm.de
Die Apoptose ist ein lebenswichtiger Prozess, ohne den es keine höher entwickelten
Lebewesen geben würde und ohne diesen ein Überleben unmöglich wäre. Apoptose findet …
Lebewesen geben würde und ohne diesen ein Überleben unmöglich wäre. Apoptose findet …
[HTML][HTML] Attention on Smoking Status to PD-1/PD-L1 Drugs on Non-Small Lung Cancer Patients
J Li, S Guo, L Wang, TZ Zhuang, M Ren… - Journal of Cancer …, 2019 - fortuneonline.org
Smoking is considered a serious risk factor for developing a large array of cardiopulmonary
conditions, in particular, squamous cell carcinoma in non-small cell lung cancer (NSCLC) …
conditions, in particular, squamous cell carcinoma in non-small cell lung cancer (NSCLC) …
Effect of Therapeutically Related Drugs on Coagulation-Anticoagulation Balance in Acute Promyelocytic Leukemia
M Xiao, P Zhou, K Sun - Clinical and Applied Thrombosis …, 2022 - journals.sagepub.com
Acute promyelocytic leukemia (APL) usually presents with a series of coagulation-
anticoagulation disturbance. Early administration of All-trans retinoic acid (ATRA) can …
anticoagulation disturbance. Early administration of All-trans retinoic acid (ATRA) can …
[PDF][PDF] Retinoic acid and arsenic trioxide induce lasting differentiation and demethylation of target genes in ApL cells
BM Cruickshank, K Lee, CY Loung, RW Holloway - researchgate.net
Methods Cell line and culture conditions. NB4 cells (obtained from DSMZ) and NB4-MR2
cells (kindly provided by Dr. Wilson Miller Jr., McGill University, Montreal, QC) 34 and …
cells (kindly provided by Dr. Wilson Miller Jr., McGill University, Montreal, QC) 34 and …
Recidiva de Leucemia Promielocítica Aguda
MF de Castro - 2018 - search.proquest.com
A leucemia promielocítica aguda (LPA) corresponde a um subtipo de leucemia mielóide
aguda em que ocorre uma translocação entre os cromossomas 15 e 17 [t (15; 17)], que …
aguda em que ocorre uma translocação entre os cromossomas 15 e 17 [t (15; 17)], que …