[HTML][HTML] Dopaminergic transmission rapidly and persistently enhances excitability of D1 receptor-expressing striatal projection neurons

AK Lahiri, MD Bevan - Neuron, 2020 - cell.com
Substantia nigra dopamine neurons have been implicated in the initiation and invigoration
of movement, presumably through their modulation of striatal projection neuron (SPN) …

Understanding neuropeptide transmission in the brain by optical uncaging and release

H Xiong, BA Wilson, PA Slesinger… - ACS chemical …, 2023 - ACS Publications
Neuropeptides are abundant and essential signaling molecules in the nervous system
involved in modulating neural circuits and behavior. Neuropeptides are generally released …

[HTML][HTML] A wireless, implantable optoelectrochemical probe for optogenetic stimulation and dopamine detection

C Liu, Y Zhao, X Cai, Y Xie, T Wang, D Cheng… - Microsystems & …, 2020 - nature.com
Physical and chemical technologies have been continuously progressing advances in
neuroscience research. The development of research tools for closed-loop control and …

Model systems for analysis of dopamine transporter function and regulation

MJ Hovde, GH Larson, RA Vaughan… - Neurochemistry …, 2019 - Elsevier
The dopamine transporter (DAT) plays a critical role in dopamine (DA) homeostasis by
clearing transmitter from the extraneuronal space after vesicular release. DAT serves as a …

[HTML][HTML] The dopamine neuron synaptic map in the striatum

N Chuhma, SJ Oh, S Rayport - Cell reports, 2023 - cell.com
Dopamine neurons project to the striatum to control movement, cognition, and motivation via
slower volume transmission as well as faster dopamine, glutamate, and GABA synaptic …

Dopamine terminals from the ventral tegmental area gate intrinsic inhibition in the prefrontal cortex

WC Buchta, SV Mahler, B Harlan… - Physiological …, 2017 - Wiley Online Library
Spike frequency adaptation (SFA or accommodation) and calcium‐activated potassium
channels that underlie after‐hyperpolarization potentials (AHP) regulate repetitive firing of …

Miniaturized Implantable Fluorescence Probes Integrated with Metal–Organic Frameworks for Deep Brain Dopamine Sensing

W Ling, X Shang, C Yu, C Li, K Xu, L Feng, Y Wei… - ACS …, 2024 - ACS Publications
Continuously monitoring neurotransmitter dynamics can offer profound insights into neural
mechanisms and the etiology of neurological diseases. Here, we present a miniaturized …

Characterization of optically and electrically evoked dopamine release in striatal slices from digenic knock-in mice with DAT-driven expression of channelrhodopsin

B O'Neill, JC Patel, ME Rice - ACS chemical neuroscience, 2017 - ACS Publications
Fast-scan cyclic voltammetry (FCV) is an established method to monitor increases in
extracellular dopamine (DA) concentration ([DA] o) in the striatum, which is densely …

Large-scale, all polycrystalline diamond structures transferred onto flexible Parylene-C films for neurotransmitter sensing

B Fan, Y Zhu, R Rechenberg, CA Rusinek, MF Becker… - Lab on a Chip, 2017 - pubs.rsc.org
Boron-doped diamond (BDD) has superior electrochemical properties for bioelectronic
systems. However, due to its high synthesis temperature, traditional microfabrication …

[HTML][HTML] DDC-promoter-driven chemogenetic activation of SNpc dopaminergic neurons alleviates parkinsonian motor symptoms

DC Seo, YH Ju, JJ Seo, SJ Oh, CJ Lee, SE Lee… - International Journal of …, 2023 - mdpi.com
Parkinson's disease (PD) is a neurodegenerative disorder with typical motor symptoms.
Recent studies have suggested that excessive GABA from reactive astrocytes tonically …