Natriuretic peptides are a family of three structurally related hormone/paracrine factors. Atrial
natriuretic peptide (ANP) and B-type natriuretic peptide (BNP) are secreted from the cardiac …

C. elegans has a highly developed chemosensory system that enables it to detect a wide
variety of volatile (olfactory) and water-soluble (gustatory) cues associated with food …

Chemosensory neurons translate perception of external chemical cues, including odorants,
tastants, and pheromones, into information that drives attraction or avoidance motor …

Because life is often unpredictable, dynamic, and complex, all animals have evolved
remarkable abilities to cope with changes in their external environment and internal …

In response to harsh environmental conditions, C. eleganslarvae undergo dauer arrest at
the second molt. The past decade has yielded many insights into the signaling pathways …

Frontotemporal dementia with parkinsonism chromosome 17 type (FTDP-17) is caused by
mutations in MAPT, the gene encoding tau. FTDP-17 begins with executive function deficits …

The growth and behavior of higher organisms depend on the accurate perception and
integration of sensory stimuli by the nervous system. We show that defects in sensory …

Despite the prevalence of obesity and its related diseases, the signaling pathways for
appetite control and satiety are not clearly understood. Here we report C. elegans …

Chemotaxis in Caenorhabditis elegans, like chemotaxis in bacteria, involves a random walk
biased by the time derivative of attractant concentration,, but how the derivative is computed …

Transforming Growth Factor-β (TGF-β) superfamily ligands regulate many aspects of cell
identity, function, and survival in multicellular animals. Genes encoding five TGF-β family …