Role of wound microbiome, strategies of microbiota delivery system and clinical management

Q Tang, N Xue, X Ding, KHY Tsai, JJ Hew… - Advanced Drug Delivery …, 2023 - Elsevier
Delayed wound healing is one of the most global public health threats affecting nearly 100
million people each year, particularly the chronic wounds. Many confounding factors such as …

[HTML][HTML] Evaluation of the role of povidone‑iodine in the prevention of surgical site infections

SJ Monstrey, K Govaers, P Lejuste, D Lepelletier… - Surgery Open …, 2023 - Elsevier
Background The occurrence of surgical site infections (SSIs) is associated with increased
risk of mortality, development of other infections, and the need for reintervention, posing a …

[HTML][HTML] Bacterial reservoir in deeper skin is a potential source for surgical site and biomaterial-associated infections

C Guarch-Pérez, M Riool, L de Boer, P Kloen… - Journal of Hospital …, 2023 - Elsevier
Background The origin of surgical site and biomaterial-associated infection is still elusive.
Micro-organisms contaminating the wound may come from the air in the operating theatre …

Meta-analysis of the efficacy of preoperative skin preparation with alcoholic chlorhexidine compared to povidone iodine in orthopedic surgery

M Mastrocola, G Matziolis, S Böhle, C Lindemann… - Scientific reports, 2021 - nature.com
Preoperative skin preparation is an effective method to prevent surgical site infections (SSI).
Alcoholic chlorhexidine (CHG) and povidone iodine (PV-I) are the most widely used …

New Insights into Cutaneous Asepsis: Synergism between Pfaffia and Rosemary Extracts

DG Miranda, F Carrouel, TCA Silva, MC Rozzatto… - Antibiotics, 2024 - mdpi.com
(1) Background: In hospitals, medical and dental clinics, antiseptics or disinfectants play an
essential role in the control of nosocomial infections. This study aimed to evaluate R …

Cutibacterium acnes Dysbiosis: Alternative Therapeutics for Clinical Application

S Sá, R Fernandes, Á Gestoso, JM Macedo… - Applied Sciences, 2023 - mdpi.com
Cutibacterium acnes (C. acnes) is a Gram-positive anaerobic facultative bacterium that is
part of the human skin commensal microbiome. It colonizes various regions of the body …

[PDF][PDF] Effectiveness of continuing post-surgery antibiotic prophylaxis in reducing nosocomial infections-A literature review

S Staicovici, V Sârbu, E Gheorghe, S Deacu… - Chir Buchar …, 2023 - revistachirurgia.ro
Context: Pentru a preveni infecţia chirurgicală, profilaxia cu antibiotice este frecvent
prelungită pentru o zi sau mai multe după intervenţiile operatorii. Profilaxia antibiotică …

Topical Preparations for Reducing Cutibacterium acnes Infections in Shoulder Surgery: A Systematic Review and Network Meta-analysis of Randomized Controlled …

Y Sewpaul, R Huynh, B Leung… - … American Journal of …, 2024 - journals.sagepub.com
Background: Cutibacterium acnes (C acnes) is a commensal skin bacterium, primarily found
in sebaceous glands and hair follicles, with a high prevalence in the shoulder region. It is the …

Formulation, Optimization, and Evaluation of Non-Propellent Foam-Based Formulation for Burn Wounds Treatment

M Kumar, S Chopra, S Mahmood, MA Mirza… - Journal of …, 2024 - Elsevier
Burn injuries worldwide pose significant health risks due to frequent microbial infections,
which worsen complications and increase mortality rates. The conventional antimicrobial …

Advanced Skin Antisepsis: Application of UVA-Cleavable Hydroxyethyl Starch Nanocapsules for Improved Eradication of Hair Follicle-Associated Microorganisms

L Busch, AM Hanuschik, Y Avlasevich, K Darm… - Pharmaceutics, 2023 - mdpi.com
Hair follicles constitute important drug delivery targets for skin antisepsis since they
contain≈ 25% of the skin microbiome. Nanoparticles are known to penetrate deeply into …