Reactive oxygen species (ROS)-based nanomedicine

B Yang, Y Chen, J Shi - Chemical reviews, 2019 - ACS Publications
Reactive oxygen species (ROS) play an essential role in regulating various physiological
functions of living organisms. The intrinsic biochemical properties of ROS, which underlie …

Reactive oxygen species (ROS)-responsive biomaterials mediate tissue microenvironments and tissue regeneration

Y Yao, H Zhang, Z Wang, J Ding, S Wang… - Journal of Materials …, 2019 - pubs.rsc.org
Reactive oxygen species (ROS) have been considered the pivotal signaling molecules in
many physiological processes, and are usually overproduced in various inflammatory …

Bioresponsive drug delivery systems for the treatment of inflammatory diseases

Y Dou, C Li, L Li, J Guo, J Zhang - Journal of Controlled Release, 2020 - Elsevier
Inflammation is intimately related to the pathogenesis of numerous acute and chronic
diseases like cardiovascular disease, inflammatory bowel disease, rheumatoid arthritis, and …

Engineering cell membrane‐based nanotherapeutics to target inflammation

H Yan, D Shao, YH Lao, M Li, H Hu… - Advanced …, 2019 - Wiley Online Library
Inflammation is ubiquitous in the body, triggering desirable immune response to defend
against dangerous signals or instigating undesirable damage to cells and tissues to cause …

Nanoparticles in the diagnosis and treatment of vascular aging and related diseases

H Xu, S Li, YS Liu - Signal Transduction and Targeted Therapy, 2022 - nature.com
Aging-induced alternations of vasculature structures, phenotypes, and functions are key in
the occurrence and development of vascular aging-related diseases. Multiple molecular and …

Nanotechnology for cardiovascular diseases

Q Hu, Z Fang, J Ge, H Li - The Innovation, 2022 - cell.com
Cardiovascular diseases have become the major killers in today's world, among which
coronary artery diseases (CADs) make the greatest contributions to morbidity and mortality …

A proresolving peptide nanotherapy for site‐specific treatment of inflammatory bowel disease by regulating proinflammatory microenvironment and gut microbiota

C Li, Y Zhao, J Cheng, J Guo, Q Zhang… - Advanced …, 2019 - Wiley Online Library
The incidence and prevalence of inflammatory bowel disease (IBD) increases steadily
worldwide. There is an urgent need for effective and safe IBD therapies. Accelerated …

Applications of nanobiomaterials in the therapy and imaging of acute liver failure

Y Jin, H Wang, K Yi, S Lv, H Hu, M Li, Y Tao - Nano-micro letters, 2021 - Springer
Highlights This review focuses on the therapeutic mechanisms, targeting strategies of
various nanomaterials in acute liver failure, and recent advances of diverse nanomaterials …

Ginsenoside Rg3-loaded, reactive oxygen species-responsive polymeric nanoparticles for alleviating myocardial ischemia-reperfusion injury

L Li, Y Wang, R Guo, S Li, J Ni, S Gao, X Gao… - Journal of Controlled …, 2020 - Elsevier
Myocardial ischemia-reperfusion injury (MIRI) is a serious threat to the health and lives of
patients without any effective therapy. Excessive production of reactive oxygen species …

Site‐specific microRNA‐33 antagonism by pH‐responsive nanotherapies for treatment of atherosclerosis via regulating cholesterol efflux and adaptive immunity

C Li, Y Dou, Y Chen, Y Qi, L Li, S Han… - Advanced functional …, 2020 - Wiley Online Library
Atherosclerosis remains the leading cause of a broad spectrum of deadliest cardiovascular
diseases. MicroRNA‐33 is a new therapeutic target for atherosclerosis due to its diverse …