Recent progress of prognostic biomarkers and risk scoring systems in chronic lymphocytic leukemia

X Yun, Y Zhang, X Wang - Biomarker research, 2020 - Springer
Chronic lymphocytic leukemia (CLL) is the most prevalent adult leukemia with high
heterogeneity in the western world. Thus, investigators identified a number of prognostic …

Biological significance of monoallelic and biallelic BIRC3 loss in del(11q) chronic lymphocytic leukemia progression

M Quijada-Álamo, M Hernández-Sánchez… - Blood Cancer …, 2021 - nature.com
BIRC3 is monoallelically deleted in up to 80% of chronic lymphocytic leukemia (CLL) cases
harboring del (11q). In addition, truncating mutations in the remaining allele of this gene can …

Integrative NGS testing reveals clonal dynamics of adverse genomic defects contributing to a natural progression in treatment‐naïve CLL patients

V Navrkalova, K Plevova, L Radova… - British Journal of …, 2024 - Wiley Online Library
Large‐scale next‐generation sequencing (NGS) studies revealed extensive genetic
heterogeneity, driving a highly variable clinical course of chronic lymphocytic leukaemia …

Immunological and genetic kinetics from diagnosis to clinical progression in chronic lymphocytic leukemia

I Jiménez, B Tazón-Vega, P Abrisqueta, JC Nieto… - Biomarker …, 2021 - Springer
Background Mechanisms driving the progression of chronic lymphocytic leukemia (CLL)
from its early stages are not fully understood. The acquisition of molecular changes at the …

Tumour immune evasion is promoted by actin cytoskeleton-driven polarization of inhibitory signals to the immunological synapse

HGA Wurzer - 2021 - orbilu.uni.lu
Natural killer (NK) cells are innate immune cells that are the first line of defence against
infection and malignant transformation. They have the ability to recognize and destroy virally …

Chronic lymphocytic leukemia: Studies from genetics to epidemiology with focus on the impact of different treatments

M Mattsson - 2020 - diva-portal.org
Chronic lymphocytic leukemia Page 1 ACTA UNIVERSITATIS UPSALIENSIS UPPSALA 2020
Digital Comprehensive Summaries of Uppsala Dissertations from the Faculty of Medicine 1684 …