The ketogenic diet (KD) is a high-fat, adequate-protein, and very-low-carbohydrate diet
regimen that mimics the metabolism of the fasting state to induce the production of ketone …

For decades, lactic acid has been considered a dead-end product of glycolysis. Research in
the last 20+ years has shown otherwise. Through its transporters (MCTs) and receptor …

Ketogenic Diet - StatPearls - NCBI Bookshelf US flag An official website of the United States
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The prevalence of type 2 diabetes (T2D) is rapidly increasing, and effective strategies to
manage and prevent this disease are urgently needed. Resistance training (RT) promotes …

Temperature is a key abiotic factor affecting ecology, biogeography, and evolution of
species. Alterations of energy metabolism play an important role in adaptations and plastic …

We have proposed that lactate is a “volume transmitter” in the brain and underpinned this by
showing that the lactate receptor, G‐protein‐coupled receptor 81 (GPR81, also known as …

Mitochondria can change their shape from discrete isolated organelles to a large continuous
reticulum. The cellular advantages underlying these fused networks are still incompletely …

Neurodegenerative disorders have been considered as a growing health concern for
decades. Increasing risk of neurodegenerative disorders creates a socioeconomic burden to …

Mitochondria play a key role in overall cell physiology and health by integrating cellular
metabolism with cellular defense and repair mechanisms in response to physiological or …

Sepsis is a complex, heterogeneous physiologic condition that represents a significant
public health concern. While many insights into the pathophysiology of sepsis have been …