Understanding enzyme mechanisms is essential for unraveling the complex molecular
machinery of life. In this review, we survey the field of computational enzymology …

L-tryptophan functionalized AgNPs were successfully fabricated using a one-pot synthesis
method and assessed as a colorimetric probe for rapid and accurate determination of Mg 2+ …

Reactions involving the transfer of a phosphoryl (− PO32–) group are fundamental to cellular
metabolism. These reactions are catalyzed by enzymes, often large and complex, belonging …

Thermogenesis is a physiological activity of releasing heat that originates from intracellular
biochemical reactions. Recent experimental studies discovered that externally applied heat …

Increasing levels of CO2 in the atmosphere have led to a growing interest into the various
ways nature transforms this greenhouse gas into valuable organic compounds. Crotonyl …

The N‐terminal transactivation domain (TAD) of p53 is a disordered region with multiple
phosphorylation sites. Phosphorylation at Thr18 is crucial for the release of p53 from its …

Crotonyl-CoA carboxylase/reductase (Ccr) is one of the fastest CO2 fixing enzymes and has
become part of efficient artificial CO2-fixation pathways in vitro, paving the way for future …

Human methionine adenosyltransferase MAT2A provides S-adenosyl-l-methionine
(AdoMet) for methyl-transfer reactions. Epigenetic methylations influence expression …

Abstract Reaction of 2-[(2-methylcarbonyl) phenyloxy]-4, 4, 5, 5-tetra-methyl-1, 3, 2-
dioxaphospholane with hexafluoroacetone leads to the simultaneous formation of two P …

Intrinsically disordered proteins (IDPs) are proteins that lack well-defined three-dimensional
structures and instead exist as dynamic ensembles of conformations. Post-translational …