PI3K/AKT/mTOR signaling in gastric cancer: Epigenetics and beyond

S Fattahi, F Amjadi-Moheb, R Tabaripour, GH Ashrafi… - Life sciences, 2020 - Elsevier
Abstract PI3K/AKT/mTOR pathway is one of the most important signaling pathways involved
in normal cellular processes. Its aberrant activation modulates autophagy, epithelial …

The emerging role of lncRNAs in cancer

M Huarte - Nature medicine, 2015 - nature.com
It is increasingly evident that many of the genomic mutations in cancer reside inside regions
that do not encode proteins. However, these regions are often transcribed into long …

LncRNA HOXA11-AS promotes proliferation and invasion of gastric cancer by scaffolding the chromatin modification factors PRC2, LSD1, and DNMT1

M Sun, F Nie, Y Wang, Z Zhang, J Hou, D He, M Xie… - Cancer research, 2016 - AACR
Long noncoding RNAs (lncRNA) have been implicated in human cancer but their
mechanisms of action are mainly undocumented. In this study, we investigated lncRNA …

Noncoding RNA s in disease

E Lekka, J Hall - FEBS letters, 2018 - Wiley Online Library
Noncoding RNA s are emerging as potent and multifunctional regulators in all biological
processes. In parallel, a rapidly growing number of studies has unravelled associations …

The small peptide world in long noncoding RNAs

SW Choi, HW Kim, JW Nam - Briefings in bioinformatics, 2019 - academic.oup.com
Long noncoding RNAs (lncRNAs) are a group of transcripts that are longer than 200
nucleotides (nt) without coding potential. Over the past decade, tens of thousands of novel …

[HTML][HTML] Interaction and cross-talk between non-coding RNAs

S Yamamura, M Imai-Sumida, Y Tanaka… - Cellular and molecular …, 2018 - Springer
Non-coding RNA (ncRNA) has been shown to regulate diverse cellular processes and
functions through controlling gene expression. Long non-coding RNAs (lncRNAs) act as a …

H3K27 acetylation activated-long non-coding RNA CCAT1 affects cell proliferation and migration by regulating SPRY4 and HOXB13 expression in esophageal …

E Zhang, L Han, D Yin, X He, L Hong, X Si… - Nucleic acids …, 2017 - academic.oup.com
Recently, long non-coding RNAs (lncRNAs) have been shown to have important regulatory
roles in human cancer biology. In our study, we found that lncRNA CCAT1, whose …

Long noncoding RNA ANRIL promotes non–small cell lung cancer cell proliferation and inhibits apoptosis by silencing KLF2 and P21 expression

F Nie, M Sun, J Yang, M Xie, T Xu, R Xia, Y Liu… - Molecular cancer …, 2015 - AACR
Recent evidence highlights long noncoding RNAs (lncRNA) as crucial regulators of cancer
biology that contribute to essential cancer cell functions such as cell proliferation, apoptosis …

[HTML][HTML] Molecular mechanisms of long noncoding RNAs on gastric cancer

T Li, X Mo, L Fu, B Xiao, J Guo - Oncotarget, 2016 - ncbi.nlm.nih.gov
Long noncoding RNAs (lncRNAs) are non-protein coding transcripts longer than 200
nucleotides. Aberrant expression of lncRNAs has been found associated with gastric cancer …

[HTML][HTML] The role of miRNA and lncRNA in gastric cancer

NB Hao, YF He, XQ Li, K Wang, RL Wang - Oncotarget, 2017 - ncbi.nlm.nih.gov
Gastric cancer is one of the most common cancers and has the highest mortality rate
worldwide. It is worthwhile to explore the mechanism of gastric cancer progression. An …