PI3K/AKT/mTOR signaling in gastric cancer: Epigenetics and beyond
S Fattahi, F Amjadi-Moheb, R Tabaripour, GH Ashrafi… - Life sciences, 2020 - Elsevier
Abstract PI3K/AKT/mTOR pathway is one of the most important signaling pathways involved
in normal cellular processes. Its aberrant activation modulates autophagy, epithelial …
in normal cellular processes. Its aberrant activation modulates autophagy, epithelial …
The emerging role of lncRNAs in cancer
M Huarte - Nature medicine, 2015 - nature.com
It is increasingly evident that many of the genomic mutations in cancer reside inside regions
that do not encode proteins. However, these regions are often transcribed into long …
that do not encode proteins. However, these regions are often transcribed into long …
LncRNA HOXA11-AS promotes proliferation and invasion of gastric cancer by scaffolding the chromatin modification factors PRC2, LSD1, and DNMT1
Long noncoding RNAs (lncRNA) have been implicated in human cancer but their
mechanisms of action are mainly undocumented. In this study, we investigated lncRNA …
mechanisms of action are mainly undocumented. In this study, we investigated lncRNA …
Noncoding RNA s in disease
E Lekka, J Hall - FEBS letters, 2018 - Wiley Online Library
Noncoding RNA s are emerging as potent and multifunctional regulators in all biological
processes. In parallel, a rapidly growing number of studies has unravelled associations …
processes. In parallel, a rapidly growing number of studies has unravelled associations …
The small peptide world in long noncoding RNAs
SW Choi, HW Kim, JW Nam - Briefings in bioinformatics, 2019 - academic.oup.com
Long noncoding RNAs (lncRNAs) are a group of transcripts that are longer than 200
nucleotides (nt) without coding potential. Over the past decade, tens of thousands of novel …
nucleotides (nt) without coding potential. Over the past decade, tens of thousands of novel …
[HTML][HTML] Interaction and cross-talk between non-coding RNAs
S Yamamura, M Imai-Sumida, Y Tanaka… - Cellular and molecular …, 2018 - Springer
Non-coding RNA (ncRNA) has been shown to regulate diverse cellular processes and
functions through controlling gene expression. Long non-coding RNAs (lncRNAs) act as a …
functions through controlling gene expression. Long non-coding RNAs (lncRNAs) act as a …
H3K27 acetylation activated-long non-coding RNA CCAT1 affects cell proliferation and migration by regulating SPRY4 and HOXB13 expression in esophageal …
E Zhang, L Han, D Yin, X He, L Hong, X Si… - Nucleic acids …, 2017 - academic.oup.com
Recently, long non-coding RNAs (lncRNAs) have been shown to have important regulatory
roles in human cancer biology. In our study, we found that lncRNA CCAT1, whose …
roles in human cancer biology. In our study, we found that lncRNA CCAT1, whose …
Long noncoding RNA ANRIL promotes non–small cell lung cancer cell proliferation and inhibits apoptosis by silencing KLF2 and P21 expression
F Nie, M Sun, J Yang, M Xie, T Xu, R Xia, Y Liu… - Molecular cancer …, 2015 - AACR
Recent evidence highlights long noncoding RNAs (lncRNA) as crucial regulators of cancer
biology that contribute to essential cancer cell functions such as cell proliferation, apoptosis …
biology that contribute to essential cancer cell functions such as cell proliferation, apoptosis …
[HTML][HTML] Molecular mechanisms of long noncoding RNAs on gastric cancer
T Li, X Mo, L Fu, B Xiao, J Guo - Oncotarget, 2016 - ncbi.nlm.nih.gov
Long noncoding RNAs (lncRNAs) are non-protein coding transcripts longer than 200
nucleotides. Aberrant expression of lncRNAs has been found associated with gastric cancer …
nucleotides. Aberrant expression of lncRNAs has been found associated with gastric cancer …
[HTML][HTML] The role of miRNA and lncRNA in gastric cancer
NB Hao, YF He, XQ Li, K Wang, RL Wang - Oncotarget, 2017 - ncbi.nlm.nih.gov
Gastric cancer is one of the most common cancers and has the highest mortality rate
worldwide. It is worthwhile to explore the mechanism of gastric cancer progression. An …
worldwide. It is worthwhile to explore the mechanism of gastric cancer progression. An …