Leber hereditary optic neuropathy (LHON) is one of the most common inherited optic
neuropathies causing bilateral central vision loss. The disorder results from point mutations …

Retinitis pigmentosa (RP) refers to a diverse group of progressive, hereditary diseases of the
retina that lead to incurable blindness and affect two million people worldwide. Artificial …

Müller glia with stem cell characteristics have been identified in the adult human eye, and
although there is no evidence that they regenerate retina in vivo, they can be induced to …

Bilateral visual loss secondary to inherited optic neuropathies is an important cause of
registrable blindness among children and young adults. The two prototypal disorders seen …

Glaucoma is a degenerative optic neuropathy characterized by retinal ganglion cell (RGC)
loss and visual field defects. It is known that in some glaucoma patients, death of RGCs …

Retinal ganglion cells (RGCs) are neurons of the visual system that are responsible for
transmitting signals from the retina to the brain via the optic nerve. Glaucoma is an optic …

Objective: To evaluate the feasibility of a new technique for the implantation of ultrathin
substrates containing stem cell-derived retinal pigment epithelium (RPE) cells into the …

Background: Retinal ganglion cells (RGCs) are the nervous retinal elements which connect
the visual receptors to the brain forming the nervous visual system. Functional and/or …

Retinitis pigmentosa (RP) is one of hereditary retinal diseases characterized by the loss of
photoreceptors. Cell transplantation has been clinically applied to treat RP patients. Human …

Importance Evidence is mounting that achromatopsia is a progressive retinal degeneration,
and treatments for this condition are on the horizon. Objectives To categorize achromatopsia …