Stimuli‐responsive materials in general and pH‐responsive polymers in particular have
gained increasing interest during the last two decades. Their unique properties, which arise …

Polymeric micelles (PMs) have been widely investigated as nanocarriers for drug delivery
and cancer treatments due to their excellent physicochemical properties, drug loading and …

Immune-checkpoint inhibitors (ICI) are promising modalities for treating triple negative
breast cancer (TNBC). However, hyperglycolysis, a hallmark of TNBC cells, may drive tumor …

Acidic extracellular pH is a major feature of tumor tissue, extracellular acidification being
primarily considered to be due to lactate secretion from anaerobic glycolysis …

Polymeric materials have been used in a range of pharmaceutical and biotechnology
products for more than 40 years. These materials have evolved from their earlier use as …

Self-assembled nanostructures of amphiphilic and double hydrophilic block copolymers
have been increasingly utilized as potent polymeric nanocarriers of therapeutic drugs …

Efficient delivery of therapeutics into tumor cells to increase the intracellular drug
concentration is a major challenge for cancer therapy due to drug resistance and inefficient …

The last decade has witnessed enormous research focused on cationic polymers. Cationic
polymers are the subject of intense research as non-viral gene delivery systems, due to their …

Abstract pH-responsive polymers contain ionic functional groups as pendants in their
structure. The total number of charged groups on polymer chains determines the overall …

Rapidly developing polymeric micelles as potential targeting carriers has intensified the
need for better understanding of the underlying principles related to the selection of suitable …