Malaria remains a leading cause of death and disease in many tropical and subtropical
regions of the world. Due to the alarming spread of resistance to almost all available …

For its replication within red blood cells, the malaria parasite depends on a highly active and
regulated lipid metabolism. Enzymes involved in lipid metabolic processes such as …

Replication of the malarial parasite in human erythrocytes requires massive zinc fluxes,
necessitating the action of zinc transporters across the parasite plasma and organellar …

Host iron deficiency is protective against severe malaria as the human malaria parasite
Plasmodium falciparum depends on bioavailable iron from its host to proliferate. The …

Background The rapid reproduction of malaria parasites requires proper iron uptake.
However, the process of iron absorption by parasites is rarely studied. Divalent metal …

Mature gametocytes of Plasmodium falciparum display a banana (falciform) shape conferred
by a complex array of subpellicular microtubules (SPMT) associated with the inner …

Malaria is responsible for hundreds of thousands of deaths every year. The lack of an
effective vaccine and the global spread of multidrug resistant parasites hampers the fight …

Artemisinins have been used as first-line drugs worldwide to treat malaria caused by
Plasmodium falciparum; however, its underlying mechanism is still unclear. This study …

Plasmodium falciparum malaria parasites invade and multiply inside red blood cells (RBCs),
the most iron-rich compartment in humans. Like all cells, P. falciparum requires nutritional …