Some have claimed that the medial prefrontal cortex (mPFC) mediates decision making.
Others suggest mPFC is selectively involved in the retrieval of remote long-term memory. Yet …

We present in this paper a picture of the neural systems controlling defense that updates
and simplifies Gray's “Neuropsychology of Anxiety”. It is based on two behavioural …

The authors present a unified account of 2 neural systems concerned with the development
and expression of adaptive behaviors: a mesencephalic dopamine system for reinforcement …

The functions of rewards are based primarily on their effects on behavior and are less
directly governed by the physics and chemistry of input events as in sensory systems …

Deciding between stimuli requires combining their learned value with one's sensory
confidence. We trained mice in a visual task that probes this combination. Mouse choices …

The medial prefrontal cortex (mPFC) and ventral hippocampus (vHPC) functionally interact
during innate anxiety tasks. To explore the consequences of this interaction, we examined …

How we decide whether a course of action is worth undertaking is largely unknown.
Recently, neuroscientists have been turning to ecological approaches to address this issue …

We conducted a series of experiments to elucidate the role of rat medial frontal cortex
(MFC)(including prelimbic, infralimbic, and cingulate cortices) in effort-based decision …

Regulation of attention and promotion of behavioural flexibility are functions attributed to
both the noradrenergic nucleus locus coeruleus (LC) and the prefrontal cortex (PFC). The …

Contextual representations serve to guide many aspects of behavior and influence the way
stimuli or actions are encoded and interpreted. The medial prefrontal cortex (mPFC) …