Deazaflavin cofactors enhance the metabolic flexibility of microorganisms by catalyzing a
wide range of challenging enzymatic redox reactions. While structurally similar to riboflavin …

Many bacteria and archaea produce the redox cofactor F420. F420 is structurally similar to
the cofactors FAD and FMN but is catalytically more similar to NAD and NADP. These …

MR1-restricted T cells (MR1Ts) are a T cell subset that recognize and mediate host defense
to a broad array of microbial pathogens, including respiratory pathogens (eg …

Hydroxylated rhodamines, carbopyronines, silico‐and germanorhodamines with absorption
maxima in the range of 530–640 nm were prepared and applied in specific labeling of living …

Deazaflavins are well suited for reductive chemistry acting via a consecutive photo‐induced
electron transfer, in which their triplet state and semiquinone–the latter is formed from the …

The deazaflavin cofactor F420 is a low-potential, two-electron redox cofactor produced by
some Archaea and Eubacteria that is involved in methanogenesis and methanotrophy …

Coenzyme F 420 is involved in bioprocesses such as biosynthesis of antibiotics by
streptomycetes, prodrug activation in Mycobacterium tuberculosis, and methanogenesis in …

The asymmetric reduction of enoates, imines and ketones are among the most important
reactions in biocatalysis. These reactions are routinely conducted using enzymes that use …

A photoenzymatic NADH regeneration system was established. The combination of
deazariboflavin as a photocatalyst with putidaredoxin reductase enabled the selective …

Developing treatments for antibiotic resistant bacterial infections is among the highest
priority public health challenges worldwide. Tetracyclines, one of the most important classes …