Despite available prevention and treatment measures, such as hydration, diuresis,
magnesium supplementation, and amifostine, renal toxicity is still one of the major dose …

The best treatment for elderly patients with advanced non–small-cell lung cancer (NSCLC)
is still debated. To guide clinical management of these patients and suggest the priorities for …

A new and revised version of this best-selling reference! For over eighteen years, best-
selling Cancer Nursing: Principles and Practice has provided oncology nurses with the latest …

Purpose: Although 48% of breast cancer patients are 65 years old or older, these older
patients are severely underrepresented in breast cancer clinical trials. This study tested …

The cellular function of p53 is complex. It is well known that p53 plays a key role in cellular
response to DNA damage. Moreover, p53 was implicated in cellular senescence, and it was …

Purpose This pooled analysis was undertaken to assess the efficacy and toxicity of adjuvant
cisplatin-based chemotherapy in elderly patients with non–small-cell lung cancer (NSCLC) …

The elderly comprise the majority of patients with cancer and are the recipients of the
greatest amount of chemotherapy. Unfortunately, there is a lack of data to make evidence …

This review explores the effectiveness and safety of cancer chemotherapy in older
individuals and outlines potential guidelines for the management of these patients. Cancer …

Over the past decade, haematological malignant diseases have been diagnosed with
increasing frequency in patients older than 65 years. The management of these diseases is …

Background: Elderly patients receiving anticancer drugs may have an increased risk to
develop treatment-related toxicities compared to their younger peers. However, a potential …