The origin story and emergence of molecular biology is muddled. The early triumphs in
bacterial genetics and the complexity of animal and plant genomes complicate an intricate …

The medial layer of the arterial wall is composed mainly of vascular smooth muscle cells
(VSMCs). Under physiological conditions, VSMCs assume a contractile phenotype, and their …

Background: Long noncoding RNAs (lncRNAs) are important regulators of biological
processes involved in vascular tissue homeostasis and disease development. The present …

Background: Vascular homeostasis is maintained by the differentiated phenotype of
vascular smooth muscle cells (VSMCs). The landscape of protein coding genes comprising …

Objective: Vascular smooth muscle cell (VSMC) plasticity plays a critical role in the
development of atherosclerosis. Long noncoding RNAs (lncRNAs) are emerging as …

Vascular smooth muscle cell (vSMC) dysfunction is a critical contributor to cardiovascular
diseases, including atherosclerosis, restenosis and vein graft failure. Recent advances have …

Rationale: The renin-angiotensin system is a complex regulatory network that maintains
normal physiological functions. The role of the renin-angiotensin system in sepsis-induced …

Non-coding RNAs (ncRNAs) regulate cell proliferation, migration, differentiation,
inflammation, metabolism of clinically important biomolecules, and other cellular processes …

Abstract N‐methyladenosine (m6A) represents a prevalent RNA modification observed in
colorectal cancer. Despite its abundance, the biological implications of m6A methylation on …

BACKGROUND: Increasing evidence suggests that long noncoding RNAs play significant
roles in vascular biology and disease development. One such long noncoding RNA, PSMB8 …