Fungal pathogens cause more than a billion human infections every year, resulting in more
than 1.6 million deaths annually. Understanding the natural history and evolutionary ecology …

Cryptococcosis is a globally distributed invasive fungal infection that is caused by species
within the genus Cryptococcus which presents substantial therapeutic challenges. Although …

The fungal pathogen Candida glabrata has emerged as a major health threat since it readily
acquires resistance to multiple drug classes, including triazoles and/or echinocandins. Thus …

Highlights•Cryptococcus has an unusual morphological transition in vivo to generate
enlarged titan cells.•Titan cells are greater than 15 μm in diameter, have a thick cell wall …

Cryptococcus neoformans is an opportunistic pathogenic yeast that causes serious
infections, most commonly of the central nervous system (CNS). C. neoformans is mainly …

Cryptococcus neoformans is a ubiquitous environmental fungus and an opportunistic
pathogen that causes fatal cryptococcal meningitis. Advances in genomics, genetics, and …

Many pathogenic fungi are dimorphic and switch between yeast and filamentous states. This
switch alters host-microbe interactions and is critical for pathogenicity. However, in …

The observation that some aspects of amoeba-fungal interactions resemble animal
phagocytic cell-fungal interactions, together with the finding that amoeba passage can …

Candida auris has become a serious threat to public health. The mechanisms of how this
fungal pathogen adapts to the mammalian host are poorly understood. Here we report the …

The ability to adapt to a changing environment provides a selective advantage to
microorganisms. In the case of many pathogens, a large change in their environment occurs …