18F-Labeling of Arenes and Heteroarenes for Applications in Positron Emission Tomography
S Preshlock, M Tredwell, V Gouverneur - Chemical reviews, 2016 - ACS Publications
Diverse radiochemistry is an essential component of nuclear medicine; this includes
imaging techniques such as positron emission tomography (PET). As such, PET can track …
imaging techniques such as positron emission tomography (PET). As such, PET can track …
Chemistry for Positron Emission Tomography: Recent Advances in 11C‐, 18F‐, 13N‐, and 15O‐Labeling Reactions
X Deng, J Rong, L Wang, N Vasdev… - Angewandte Chemie …, 2019 - Wiley Online Library
Positron emission tomography (PET) is a molecular imaging technology that provides
quantitative information about function and metabolism in biological processes in vivo for …
quantitative information about function and metabolism in biological processes in vivo for …
Click chemistry and radiochemistry: the first 10 years
JP Meyer, P Adumeau, JS Lewis… - Bioconjugate …, 2016 - ACS Publications
The advent of click chemistry has had a profound influence on almost all branches of
chemical science. This is particularly true of radiochemistry and the synthesis of agents for …
chemical science. This is particularly true of radiochemistry and the synthesis of agents for …
Fluorine-18 labelled building blocks for PET tracer synthesis
D Van Der Born, A Pees, AJ Poot, RVA Orru… - Chemical Society …, 2017 - pubs.rsc.org
Positron emission tomography (PET) is an important driver for present day healthcare.
Fluorine-18 is the most widely used radioisotope for PET imaging and a thorough overview …
Fluorine-18 is the most widely used radioisotope for PET imaging and a thorough overview …
Integrating DNA nanotechnology with aptamers for biological and biomedical applications
Z Huang, L Qiu, T Zhang, W Tan - Matter, 2021 - cell.com
In addition to critical biological roles, DNA is also considered an excellent engineering
material with unique characteristics of high programmability and addressability. Recent …
material with unique characteristics of high programmability and addressability. Recent …
Advances in aptamer-based nuclear imaging
Aptamers are short oligonucleotides that bind to specific target molecules. They have been
extensively explored in biomedical applications, including biosensing, medical imaging, and …
extensively explored in biomedical applications, including biosensing, medical imaging, and …
Recent advances in bioorthogonal click chemistry for enhanced PET and SPECT radiochemistry
X Zhong, J Yan, X Ding, C Su, Y Xu… - Bioconjugate …, 2023 - ACS Publications
Due to their high reaction rate and reliable selectivity, bioorthogonal click reactions have
been extensively investigated in numerous research fields, such as nanotechnology, drug …
been extensively investigated in numerous research fields, such as nanotechnology, drug …
Recent progress in the application of iodonium ylides in organic synthesis
X Mi, C Pi, W Feng, X Cui - Organic Chemistry Frontiers, 2022 - pubs.rsc.org
Iodonium ylides have attracted considerable attention due to their unique properties and
numerous applications as versatile and sustainable reagents in organic synthesis …
numerous applications as versatile and sustainable reagents in organic synthesis …
Molecular elucidation of disease biomarkers at the interface of chemistry and biology
Disease-related biomarkers are objectively measurable molecular signatures of
physiological status that can serve as disease indicators or drug targets in clinical diagnosis …
physiological status that can serve as disease indicators or drug targets in clinical diagnosis …
Mechanistic studies and radiofluorination of structurally diverse pharmaceuticals with spirocyclic iodonium (III) ylides
Synthesis of non-activated electron-rich and sterically hindered 18F-arenes remains a major
challenge due to limitations of existing radiofluorination methodologies. Herein, we report on …
challenge due to limitations of existing radiofluorination methodologies. Herein, we report on …