Targeting of cancer cell death mechanisms by curcumin: implications to cancer therapy

C Yu, B Yang, M Najafi - Basic & clinical pharmacology & …, 2021 - Wiley Online Library
Cancer is known as a second major cause of death globally. Nowadays, several modalities
have been developed for the treatment of cancer. Radiotherapy and chemotherapy are the …

Curcumin in the treatment of urological cancers: Therapeutic targets, challenges and prospects

M Hashemi, S Mirzaei, M Barati, ES Hejazi… - Life sciences, 2022 - Elsevier
Urological cancers include bladder, prostate and renal cancers that can cause death in
males and females. Patients with urological cancers are mainly diagnosed at an advanced …

[HTML][HTML] Curcumin and its novel formulations for the treatment of hepatocellular carcinoma: new trends and future perspectives in cancer therapy

SM Meybodi, P Rezaei, N Faraji… - Journal of Functional …, 2023 - Elsevier
Hepatocellular carcinoma (HCC), as a common malignancy of the liver, is the second
leading cause of cancer-related death in the world and mostly occurs in patients with a …

[HTML][HTML] Curcumin: Reclaiming the lost ground against cancer resistance

S Shaikh, J Shaikh, YS Naba, K Doke… - Cancer Drug …, 2021 - ncbi.nlm.nih.gov
Curcumin, a polyphenol, has a wide range of biological properties such as anticancer,
antibacterial, antitubercular, cardioprotective and neuroprotective. Moreover, the anti …

Curcumin and cancer biology: Focusing regulatory effects in different signalling pathways

M Bhatia, M Bhalerao, N Cruz‐Martins… - Phytotherapy …, 2021 - Wiley Online Library
Cancer is the second‐leading cause of death worldwide. Till date, many such effective
treatments are available, for example chemotherapy, surgery, and radiation therapy, but …

Curcumin sensitises cancerous kidney cells to TRAIL induced apoptosis via let-7C mediated deregulation of cell cycle proteins and cellular metabolism

I Obaidi, A Blanco Fernandez, T McMorrow - International journal of …, 2022 - mdpi.com
Targeted therapies are the most attractive options in the treatment of different tumours,
including kidney cancers. Such therapies have entered a golden era due to advancements …

Evolution of natural product scaffolds as potential proteasome inhibitors in developing cancer therapeutics

RH Mir, PA Mir, J Uppal, A Chawla, M Patel, F Bardakci… - Metabolites, 2023 - mdpi.com
Homeostasis between protein synthesis and degradation is a critical biological function
involving a lot of precise and intricate regulatory systems. The ubiquitin-proteasome …

The second‐generation curcumin analogue RL71 elicits G2/M cell cycle arrest and apoptosis in canine osteosarcoma cells

B Kelly, D Thamm, RJ Rosengren - … and Comparative Oncology, 2023 - Wiley Online Library
Canine osteosarcoma is an aggressive cancer, comprising 85% of canine bone neoplasms.
Current treatment practices of surgery and chemotherapy increase 1‐year survival by only …

[HTML][HTML] The antiviral potential of algal-derived macromolecules

J Liu, I Obaidi, S Nagar, G Scalabrino… - Current Research in …, 2021 - Elsevier
A diverse range of molecules with anticancer, antiviral, and antibiotic activities has been
identified and isolated from algal species. Such metabolites could address unmet clinical …

Exploiting polyphenol-mediated redox reorientation in cancer therapy

L Li, P Jin, Y Guan, M Luo, Y Wang, B He, B Li, K He… - Pharmaceuticals, 2022 - mdpi.com
Polyphenol, one of the major components that exert the therapeutic effect of Chinese herbal
medicine (CHM), comprises several categories, including flavonoids, phenolic acids, lignans …