The ability to design efficient enzymes from scratch would have a profound effect on
chemistry, biotechnology and medicine. Rapid progress in protein engineering over the past …

Benefiting from the impressive increase in fundamental knowledge, the last 20 years have
shown a continuous burst of new ideas and consequently a plethora of new catalytic …

The concept of strain in organic compounds is as old as modern organic chemistry and was
initially introduced to justify the synthetic setbacks along the synthesis of small ring systems …

The fields of C–H functionalization and photoredox catalysis have garnered enormous
interest and utility in the past several decades. Many different scientific disciplines have …

Radical intermediates in organic chemistry lack a full octet of electrons and, thus, are
commonly said to be electron deficient. By denotation, such a statement is technically …

Visible‐light photocatalysis has evolved over the last decade into a widely used method in
organic synthesis. Photocatalytic variants have been reported for many important …

Enzymes are characteristic of catalytic efficiency and specificity by maneuvering multiple
components in concert at a confined nanoscale space. However, achieving such a …

Conspectus The direct transformation of C–H bonds into diverse functional groups
represents one of the most atom-and step-economical strategies for organic synthesis and …

In recent years, photoredox catalysis has come to the forefront in organic chemistry as a
powerful strategy for the activation of small molecules. In a general sense, these approaches …

While organic electrochemistry can look quite different to a chemist not familiar with the
technique, the reactions are at their core organic reactions. As such, they are developed and …