Borderline personality disorder

JG Gunderson, SC Herpertz, AE Skodol… - Nature reviews disease …, 2018 - nature.com
Caretakers are often intimidated or alienated by patients with borderline personality disorder
(BPD), compounding the clinical challenges posed by the severe morbidity, high social costs …

[HTML][HTML] Borderline personality disorder and childhood trauma: exploring the affected biological systems and mechanisms

N Cattane, R Rossi, M Lanfredi, A Cattaneo - BMC psychiatry, 2017 - Springer
Background According to several studies, the onset of the Borderline Personality Disorder
(BPD) depends on the combination between genetic and environmental factors (GxE), in …

Understanding the molecular mechanisms underpinning gene by environment interactions in psychiatric disorders: the FKBP5 model

N Matosin, T Halldorsdottir, EB Binder - Biological psychiatry, 2018 - Elsevier
Epidemiologic and genetic studies suggest common environmental and genetic risk factors
for a number of psychiatric disorders, including depression, bipolar disorder, and …

[HTML][HTML] The role of trauma in early onset borderline personality disorder: a biopsychosocial perspective

P Bozzatello, P Rocca, L Baldassarri, M Bosia… - Frontiers in …, 2021 - frontiersin.org
The role of childhood trauma in the development of borderline personality disorder (BPD) in
young age has long been studied. The most accurate theoretical models are multifactorial …

[HTML][HTML] Borderline personality disorder: Risk factors and early detection

P Bozzatello, C Garbarini, P Rocca, S Bellino - Diagnostics, 2021 - mdpi.com
Personality disorders (PDs) exert a great toll on health resources, and this is especially true
for borderline personality disorder (BPD). As all PDs, BPD arises during adolescence or …

Early adverse experience and substance addiction: dopamine, oxytocin, and glucocorticoid pathways

S Kim, S Kwok, LC Mayes, MN Potenza… - Annals of the New …, 2017 - Wiley Online Library
Substance addiction may follow a chronic, relapsing course and critically undermine the
physical and psychological well‐being of the affected individual and the social units of which …

Borderline personality disorder in patients with medical illness: a review of assessment, prevalence, and treatment options

S Doering - Psychosomatic medicine, 2019 - journals.lww.com
Objective Borderline personality disorder (BPD) occurs in 0.7% to 3.5% of the general
population. Patients with BPD experience excessive comorbidity of psychiatric and somatic …

[HTML][HTML] Role of FKBP5 and its genetic mutations in stress-induced psychiatric disorders: an opportunity for drug discovery

M Malekpour, D Shekouh, ME Safavinia… - Frontiers in …, 2023 - frontiersin.org
Stress-induced mental health disorders are affecting many people around the world.
However, effective drug therapy for curing psychiatric diseases does not occur sufficiently …

Psychiatric symptoms in patients with Cushing's syndrome: prevalence, diagnosis and management

A Santos, E Resmini, JC Pascual, I Crespo, SM Webb - Drugs, 2017 - Springer
Cushing's syndrome (CS) results from chronic exposure to cortisol excess, produced by the
adrenal cortex. Hypercortisolism predisposes to psychiatric and neurocognitive disorders …

Pathoetiology and pathophysiology of borderline personality: Role of prenatal factors, gut microbiome, mu-and kappa-opioid receptors in amygdala-PFC interactions

G Anderson - Progress in Neuro-Psychopharmacology and …, 2020 - Elsevier
The pathoetiology and pathophysiology of borderline personality disorder (BPD) have been
relatively under-explored. Consequently, no targetted pharmaceutical treatments or …