Radiopharmaceuticals for PET and SPECT imaging: a literature review over the last decade

G Crișan, NS Moldovean-Cioroianu… - International journal of …, 2022 - mdpi.com
Positron emission tomography (PET) uses radioactive tracers and enables the functional
imaging of several metabolic processes, blood flow measurements, regional chemical …

Review on 99mTc radiopharmaceuticals with emphasis on new advancements

A Duatti - Nuclear medicine and biology, 2021 - Elsevier
Rapid imaging acquisition, high spatial resolution and sensitivity, powered by
advancements in solid-state detector technology, are significantly changing the perspective …

Quantification of macrophage-driven inflammation during myocardial infarction with 18F-LW223, a novel TSPO radiotracer with binding independent of the rs6971 …

MG MacAskill, A Stadulyte, L Williams… - Journal of Nuclear …, 2021 - Soc Nuclear Med
Myocardial infarction (MI) is one of the leading causes of death worldwide, and inflammation
is central to tissue response and patient outcomes. The 18-kDa translocator protein (TSPO) …

Radioactive polymeric nanoparticles for biomedical application

S Wu, E Helal-Neto, APS Matos, A Jafari… - Drug Delivery, 2020 - Taylor & Francis
Nowadays, emerging radiolabeled nanosystems are revolutionizing medicine in terms of
diagnostics, treatment, and theranostics. These radionuclides include polymeric …

Druggability of Targets for Diagnostic Radiopharmaceuticals

X Wang, C Chen, J Yan, Y Xu, D Pan… - ACS Pharmacology & …, 2023 - ACS Publications
Targets play an indispensable and pivotal role in the development of radiopharmaceuticals.
However, the initial stages of drug discovery projects are often plagued by frequent failures …

[HTML][HTML] Nuclear medicine imaging methods of radiation-induced cardiotoxicity

EAS Polomski, ML Antoni, JW Jukema, JR Kroep… - Seminars in Nuclear …, 2022 - Elsevier
Breast cancer survival is significantly improved over the past decades due to major
improvements in anti-tumor therapies and the implementation of regular screening, which …

Unlocking the Hidden Depths: Multi-Modal Integration of Imaging Mass Spectrometry-Based and Molecular Imaging Techniques

B Akbari, BR Huber, JH Sherman - Critical Reviews in Analytical …, 2023 - Taylor & Francis
Multimodal imaging (MMI) has emerged as a powerful tool in clinical research, combining
different imaging modes to acquire comprehensive information and enabling scientists and …

A clinically translatable kit for MRI/NMI dual-modality nanoprobes based on anchoring group-mediated radiolabeling

L Chen, Y Gao, J Ge, Y Zhou, Z Yang, C Li, B Huang… - Nanoscale, 2023 - pubs.rsc.org
Magnetic resonance imaging (MRI)/nuclear medicine imaging (NMI) dual-modality imaging
based on radiolabeled nanoparticles has been increasingly exploited for accurate diagnosis …

First Validation of Myocardial Flow Reserve Derived from Dynamic 99mTc-Sestamibi CZT-SPECT Camera Compared with 13N-Ammonia PET A Pilot Study

A Yamamoto, M Nagao, K Ando, R Nakao… - International Heart …, 2022 - jstage.jst.go.jp
Summary 13N-ammonia positron emission tomography (NH3-PET) can evaluate myocardial
blood flow (MBF) at rest, stress, and myocardial flow reserve (MFR) as well as the ratio of …

Radiotracers to address unmet clinical needs in cardiovascular imaging, Part 1: Technical considerations and perfusion and neuronal imaging

JC Stendahl, JM Kwan, D Pucar… - Journal of Nuclear …, 2022 - Soc Nuclear Med
The development of new radiotracers for PET and SPECT is central to addressing unmet
diagnostic needs related to systemwide trends toward molecular characterization and …