Cortisol and corticosterone act on the appraisal process, which comprises the selection of
an appropriate coping style and the encoding of the experience for storage in the memory …

Stress exposure activates the HPA-axis and results in the release of corticosteroids which
bind to two receptor types in the brain: the mineralocorticoid receptor (MR) and the …

Adolescence is characterized by major biological, psychological, and social challenges, as
well as by an increase in depression rates. This review focuses on the association between …

Recent meta-analyses have stimulated an active debate on whether the serotonin
transporter gene-linked polymorphic region (5-HTTLPR) is associated with an elevated …

Objective: The amygdala is especially reactive to threatening stimuli, and the degree of
reactivity predicts individual differences in the expression of depression and anxiety …

OBJECTIVES: The objectives of this study were as follows: to present a concise overview of
the sample, outcomes, determinants, non-response and attrition of the ongoing TRacking …

The intrauterine environment can impact the developing infant by altering the function of the
placenta through changes to the epigenetic regulatory features of this tissue. Genetic …

Clinical and epidemiological studies, further supported by meta-analytic studies, indicate a
possible association between chronicity (ie, persistence or recurrence) of depression and …

Background In adults, hypothalamus–pituitary–adrenal (HPA) axis activity shows sexual
dimorphism, and this is thought to be a mechanism underlying sex-specific disease …

Background. Hopes to identify genetic susceptibility loci accounting for the heritability seen
in unipolar depression have not been fully realized. Family history remains the 'gold …