The integrated genomics of crop domestication and breeding
X Huang, S Huang, B Han, J Li - Cell, 2022 - cell.com
As a major event in human civilization, wild plants were successfully domesticated to be
crops, largely owing to continuing artificial selection. Here, we summarize new discoveries …
crops, largely owing to continuing artificial selection. Here, we summarize new discoveries …
Addressing research bottlenecks to crop productivity
Asymmetry of investment in crop research leads to knowledge gaps and lost opportunities to
accelerate genetic gain through identifying new sources and combinations of traits and …
accelerate genetic gain through identifying new sources and combinations of traits and …
DNA methylation-free Arabidopsis reveals crucial roles of DNA methylation in regulating gene expression and development
L He, H Huang, M Bradai, C Zhao, Y You, J Ma… - Nature …, 2022 - nature.com
A contribution of DNA methylation to defense against invading nucleic acids and
maintenance of genome integrity is uncontested; however, our understanding of the extent …
maintenance of genome integrity is uncontested; however, our understanding of the extent …
The genetic and epigenetic landscape of the Arabidopsis centromeres
INTRODUCTION The centromeres of eukaryotic chromosomes assemble the multiprotein
kinetochore complex and thereby position attachment to the spindle microtubules, allowing …
kinetochore complex and thereby position attachment to the spindle microtubules, allowing …
Nucleosomes and DNA methylation shape meiotic DSB frequency in Arabidopsis thaliana transposons and gene regulatory regions
Meiotic recombination initiates from DNA double-strand breaks (DSBs) generated by SPO11
topoisomerase-like complexes. Meiotic DSB frequency varies extensively along eukaryotic …
topoisomerase-like complexes. Meiotic DSB frequency varies extensively along eukaryotic …
Double-edged sword: the evolutionary consequences of the epigenetic silencing of transposable elements
Transposable elements (TEs) are genomic parasites that selfishly replicate at the expense of
host fitness. Fifty years of evolutionary studies of TEs have concentrated on the deleterious …
host fitness. Fifty years of evolutionary studies of TEs have concentrated on the deleterious …
Patterns, mechanisms, and consequences of homoeologous exchange in allopolyploid angiosperms: a genomic and epigenomic perspective
Allopolyploids result from hybridization between different evolutionary lineages coupled with
genome doubling. Homoeologous chromosomes (chromosomes with common shared …
genome doubling. Homoeologous chromosomes (chromosomes with common shared …
Intragenomic rDNA variation-the product of concerted evolution, mutation, or something in between?
The classical model of concerted evolution states that hundreds to thousands of ribosomal
DNA (rDNA) units undergo homogenization, making the multiple copies of the individual …
DNA (rDNA) units undergo homogenization, making the multiple copies of the individual …
[HTML][HTML] Counting on crossovers: controlled recombination for plant breeding
Crossovers (COs), that drive genetic exchange between homologous chromosomes, are
strongly biased toward subtelomeric regions in plant species. Manipulating the rate and …
strongly biased toward subtelomeric regions in plant species. Manipulating the rate and …
The megabase-scale crossover landscape is largely independent of sequence divergence
Q Lian, V Solier, B Walkemeier, S Durand… - Nature …, 2022 - nature.com
Meiotic recombination frequency varies along chromosomes and strongly correlates with
sequence divergence. However, the causal relationship between recombination landscapes …
sequence divergence. However, the causal relationship between recombination landscapes …