AT-rich region and repeated sequences–the essential elements of replication origins of bacterial replicons

M Rajewska, K Wegrzyn… - FEMS microbiology …, 2012 - academic.oup.com
Repeated sequences are commonly present in the sites for DNA replication initiation in
bacterial, archaeal, and eukaryotic replicons. Those motifs are usually the binding places for …

Mechanisms of theta plasmid replication

J Lilly, M Camps - Microbiology spectrum, 2015 - Am Soc Microbiol
Plasmids are autonomously replicating pieces of DNA. This article discusses theta plasmid
replication, which is a class of circular plasmid replication that includes ColE1-like origins of …

A checkpoint control orchestrates the replication of the two chromosomes of Vibrio cholerae

ME Val, M Marbouty, F de Lemos Martins… - Science …, 2016 - science.org
Bacteria with multiple chromosomes represent up to 10% of all bacterial species. Unlike
eukaryotes, these bacteria use chromosome-specific initiators for their replication. In all …

Cell cycle-coordinated maintenance of the Vibrio bipartite genome

T Niault, J Czarnecki, M Lambérioux, D Mazel… - EcoSal …, 2023 - Am Soc Microbiol
To preserve the integrity of their genome, bacteria rely on several genome maintenance
mechanisms that are co-ordinated with the cell cycle. All members of the Vibrio family have a …

Replicate once per cell cycle: replication control of secondary chromosomes

F Fournes, ME Val, O Skovgaard, D Mazel - Frontiers in microbiology, 2018 - frontiersin.org
Faithful vertical transmission of genetic information, especially of essential core genes, is a
prerequisite for bacterial survival. Hence, replication of all the replicons is tightly controlled …

Chromosome I Controls Chromosome II Replication in Vibrio cholerae

JH Baek, DK Chattoraj - PLoS genetics, 2014 - journals.plos.org
Control of chromosome replication involves a common set of regulators in eukaryotes,
whereas bacteria with divided genomes use chromosome-specific regulators. How bacterial …

The replication enhancer crtS depends on transcription factor Lrp for modulating binding of initiator RctB to ori2 of Vibrio cholerae

A Doan, S Chatterjee, R Kothapalli, Z Khan… - Nucleic acids …, 2024 - academic.oup.com
Replication of Vibrio cholerae chromosome 2 (Chr2) initiates when the Chr1 locus, crtS (C
hr2 r eplication t riggering s ite) duplicates. The site binds the Chr2 initiator, RctB, and the …

A conformational switch between transcriptional repression and replication initiation in the RepA dimerization domain

R Giraldo, C Fernández-Tornero, PR Evans… - Nature Structural & …, 2003 - nature.com
Plasmids are natural vectors for gene transfer. In Gram-negative bacteria, plasmid DNA
replication is triggered when monomers of an initiator protein (Rep) bind to direct repeats at …

Common domains in the initiators of DNA replication in Bacteria, Archaea and Eukarya: combined structural, functional and phylogenetic perspectives

R Giraldo - FEMS microbiology reviews, 2003 - academic.oup.com
Although DNA replication is the universal process for the transmission of genetic information
in all living organisms, until very recently evidence was lacking for a related structure and …

Plasmid R6K replication control

SA Rakowski, M Filutowicz - Plasmid, 2013 - Elsevier
The focus of this minireview is the replication control of the 39.9-kb plasmid R6K and its
derivatives. Historically, this plasmid was thought to have a narrow host range but more …