A review of the current therapies, challenges, and future directions of transcranial focused ultrasound technology: advances in diagnosis and treatment

V Krishna, F Sammartino, A Rezai - JAMA neurology, 2018 - jamanetwork.com
Importance Magnetic resonance imaging–guided focused ultrasound ablation has been
approved for the treatment of refractory essential tremor and is being studied for other …

Role of the dorsal anterior cingulate cortex in obsessive-compulsive disorder: converging evidence from cognitive neuroscience and psychiatric neurosurgery

RA McGovern, SA Sheth - Journal of neurosurgery, 2017 - thejns.org
OBJECTIVE Advances in understanding the neurobiological basis of psychiatric disorders
will improve the ability to refine neuromodulatory procedures for treatment-refractory …

A unified functional network target for deep brain stimulation in obsessive-compulsive disorder

N Li, B Hollunder, JC Baldermann, A Kibleur, S Treu… - Biological …, 2021 - Elsevier
Background Multiple deep brain stimulation (DBS) targets have been proposed for treating
intractable obsessive-compulsive disorder (OCD). Here, we investigated whether stimulation …

The relevance of skull density ratio in selecting candidates for transcranial MR-guided focused ultrasound

A Boutet, D Gwun, R Gramer, M Ranjan… - Journal of …, 2019 - thejns.org
OBJECTIVE Transcranial MR-guided focused ultrasound (MRgFUS) is a minimally invasive
treatment for movement disorders. Considerable interpatient variability in skull transmission …

Opening the blood-brain barrier with MR imaging–guided focused ultrasound: Preclinical testing on a trans–human skull porcine model

Y Huang, R Alkins, ML Schwartz, K Hynynen - Radiology, 2017 - pubs.rsna.org
Purpose To develop and test a protocol in preparation for a clinical trial on opening the
blood-brain barrier (BBB) with magnetic resonance (MR) imaging–guided focused …

Cost‐effectiveness of focused ultrasound, radiosurgery, and DBS for essential tremor

VK Ravikumar, JJ Parker, TS Hornbeck… - Movement …, 2017 - Wiley Online Library
Background Essential tremor remains a very common yet medically refractory condition. A
recent phase 3 study demonstrated that magnetic resonance‐guided focused ultrasound …

Focused ultrasound–mediated noninvasive blood-brain barrier modulation: preclinical examination of efficacy and safety in various sonication parameters

J Shin, C Kong, JS Cho, J Lee, CS Koh, MS Yoon… - Neurosurgical …, 2018 - thejns.org
OBJECTIVE The application of pharmacological therapeutics in neurological disorders is
limited by the ability of these agents to penetrate the blood-brain barrier (BBB). Focused …

Unilateral magnetic resonance–guided focused ultrasound pallidotomy for Parkinson disease

YC Na, WS Chang, HH Jung, EJ Kweon, JW Chang - Neurology, 2015 - AAN Enterprises
Unilateral pallidotomy has been accepted as an efficacious treatment for Parkinson disease
(PD) compared with medical therapies. 1 Currently, magnetic resonance–guided focused …

Focused ultrasound thalamotomy for refractory essential tremor: a Japanese multicenter single-arm study

K Abe, S Horisawa, T Yamaguchi, H Hori… - …, 2021 - journals.lww.com
BACKGROUND Several feasibility studies and a randomized, controlled, multicenter trial
have demonstrated the safety and efficacy of unilateral transcranial magnetic resonance …

[HTML][HTML] Focused ultrasound for essential tremor: review of the evidence and discussion of current hurdles

M Rohani, A Fasano - Tremor and Other Hyperkinetic Movements, 2017 - ncbi.nlm.nih.gov
Background While there is no breakthrough progress in the medical treatment of essential
tremor (ET), in the past decades several remarkable achievements happened in the surgical …