Increasing evidence suggests that activation of the complement system plays a key role in
the pathogenesis and disease severity of Coronavirus disease 2019 (COVID-19). We used a …

The term “intracellular complement” has been introduced recently as an umbrella term to
distinguish functions of complement proteins that take place intracellularly, rather than in the …

The complement component C3 is a fundamental plasma protein for host defense, produced
largely by the liver. However, recent work has demonstrated the critical importance of tissue …

Rationale: The incidence and sites of mucus accumulation and molecular regulation of
mucin gene expression in coronavirus (COVID-19) lung disease have not been reported …

T cells play a fundamental role in the early control and clearance of many viral infections of
the respiratory system. In SARS-CoV-2-infected individuals, lymphopenia with drastically …

Patients with severe COVID-19 develop acute respiratory distress syndrome (ARDS) that
may progress to cytokine storm syndrome, organ dysfunction, and death. Considering that …

This article is part of the Dendritic Cell Guidelines article series, which provides a collection
of state‐of‐the‐art protocols for the preparation, phenotype analysis by flow cytometry …

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus was identified in
China in 2019 as the causative agent of COVID-19, and quickly spread throughout the …

How does SARS-CoV-2 cause lung microenvironment disturbance and inflammatory storm
is still obscure. We here performed the single-cell transcriptome sequencing from lung …

Age-related macular degeneration (AMD) and related macular dystrophies (MDs) primarily
affect the retinal pigment epithelium (RPE) in the eye. A hallmark of AMD/MDs that drives …