[HTML][HTML] Reward signals in the cerebellum: origins, targets, and functional implications
D Kostadinov, M Häusser - Neuron, 2022 - cell.com
The cerebellum has long been proposed to play a role in cognitive function, although this
has remained controversial. This idea has received renewed support with the recent …
has remained controversial. This idea has received renewed support with the recent …
Distributed synergistic plasticity and cerebellar learning
Z Gao, BJ Van Beugen, CI De Zeeuw - Nature Reviews Neuroscience, 2012 - nature.com
Studies on synaptic plasticity in the context of learning have been dominated by the view
that a single, particular type of plasticity forms the underlying mechanism for a particular type …
that a single, particular type of plasticity forms the underlying mechanism for a particular type …
Spatiotemporal firing patterns in the cerebellum
CI De Zeeuw, FE Hoebeek, LWJ Bosman… - Nature Reviews …, 2011 - nature.com
Neurons are generally considered to communicate information by increasing or decreasing
their firing rate. However, in principle, they could in addition convey messages by using …
their firing rate. However, in principle, they could in addition convey messages by using …
Motor learning and the cerebellum
CI De Zeeuw, MM Ten Brinke - Cold Spring Harbor …, 2015 - cshperspectives.cshlp.org
Although our ability to store semantic declarative information can nowadays be readily
surpassed by that of simple personal computers, our ability to learn and express procedural …
surpassed by that of simple personal computers, our ability to learn and express procedural …
[HTML][HTML] Evolving models of pavlovian conditioning: cerebellar cortical dynamics in awake behaving mice
MM Ten Brinke, HJ Boele, JK Spanke, JW Potters… - Cell reports, 2015 - cell.com
Three decades of electrophysiological research on cerebellar cortical activity underlying
Pavlovian conditioning have expanded our understanding of motor learning in the brain …
Pavlovian conditioning have expanded our understanding of motor learning in the brain …
Shared synaptic pathophysiology in syndromic and nonsyndromic rodent models of autism
SJ Baudouin, J Gaudias, S Gerharz, L Hatstatt, K Zhou… - Science, 2012 - science.org
The genetic heterogeneity of autism poses a major challenge for identifying mechanism-
based treatments. A number of rare mutations are associated with autism, and it is unclear …
based treatments. A number of rare mutations are associated with autism, and it is unclear …
[HTML][HTML] Reevaluating the role of LTD in cerebellar motor learning
Long-term depression at parallel fiber-Purkinje cell synapses (PF-PC LTD) has been
proposed to be required for cerebellar motor learning. To date, tests of this hypothesis have …
proposed to be required for cerebellar motor learning. To date, tests of this hypothesis have …
[HTML][HTML] A neural circuit state change underlying skilled movements
In motor neuroscience, state changes are hypothesized to time-lock neural assemblies
coordinating complex movements, but evidence for this remains slender. We tested whether …
coordinating complex movements, but evidence for this remains slender. We tested whether …
Timing and plasticity in the cerebellum: focus on the granular layer
E D'Angelo, CI De Zeeuw - Trends in neurosciences, 2009 - cell.com
Two of the most striking properties of the cerebellum are its control in timing of motor
operations and its ability to adapt behavior to new sensorimotor associations. Here, we …
operations and its ability to adapt behavior to new sensorimotor associations. Here, we …
Why do we move to the beat? A multi-scale approach, from physical principles to brain dynamics
L Damm, D Varoqui, VC De Cock, S Dalla Bella… - Neuroscience & …, 2020 - Elsevier
Humans' ability to synchronize movement with auditory rhythms relies on motor networks,
such as cortical areas, basal ganglia and the cerebellum, which also participate in rhythm …
such as cortical areas, basal ganglia and the cerebellum, which also participate in rhythm …