Traumatic brain injury: progress and challenges in prevention, clinical care, and research

AIR Maas, DK Menon, GT Manley, M Abrams… - The Lancet …, 2022 - thelancet.com
Executive summary Traumatic brain injury (TBI) has the highest incidence of all common
neurological disorders, and poses a substantial public health burden. TBI is increasingly …

Applications and mechanisms of stimuli-responsive hydrogels in traumatic brain injury

X Li, L Duan, M Kong, X Wen, F Guan, S Ma - Gels, 2022 - mdpi.com
Traumatic brain injury (TBI) is a global neurotrauma with high morbidity and mortality that
seriously threatens the life quality of patients and causes heavy burdens to families …

Occupational therapy practice guidelines for adults with traumatic brain injury

S Wheeler, A Acord-Vira - The American Journal of Occupational …, 2023 - research.aota.org
Importance: Occupational therapy practitioners are uniquely qualified to address the
occupational needs of people with traumatic brain injury (TBI) and their caregivers to …

Current and potential pharmacologic therapies for traumatic brain injury

J Tani, YT Wen, CJ Hu, JY Sung - Pharmaceuticals, 2022 - mdpi.com
The present article reviewed the pharmacologic therapies of traumatic brain injury (TBI),
including current and potential treatments. Pharmacologic therapies are an essential part of …

[HTML][HTML] Mitochondrial dysfunction underlies impaired neurovascular coupling following traumatic brain injury

G Van Hameren, J Muradov, A Minarik… - Neurobiology of …, 2023 - Elsevier
Traumatic brain injury (TBI) involves an acute injury (primary damage), which may evolve in
the hours to days after impact (secondary damage). Seizures and cortical spreading …

Pre-traumatic antibiotic-induced microbial depletion reduces neuroinflammation in acute murine traumatic brain injury

K Ritter, D Vetter, I Wernersbach, T Schwanz… - …, 2023 - Elsevier
The connection between dysbiosis of the gut microbiome and diseases and injuries of the
brain has attracted considerable interest in recent years. Interestingly, antibiotic-induced …

An understated comorbidity: the impact of homelessness on traumatic brain injury

M Monsour, JY Lee, CV Borlongan - Neurotherapeutics, 2023 - Springer
Traumatic brain injury (TBI), a neurovascular injury caused by external force, is a common
diagnosis among veterans and those experiencing homelessness (HL). There is a …

Anacardic acid improves neurological deficits in traumatic brain injury by anti-ferroptosis and anti-inflammation

Y Liu, Z Zhao, J Guo, Y Ma, J Li, H Ji, Z Chen… - Experimental …, 2023 - Elsevier
Background Traumatic brain injury (TBI) is an important cause of disability and death. TBI
leads to multiple forms of nerve cell death including ferroptosis due to iron-dependent lipid …

Application of P7C3 compounds to investigating and treating acute and chronic traumatic brain injury

PS Sridharan, E Miller, AA Pieper - Neurotherapeutics, 2023 - Elsevier
Traumatic brain injury (TBI) is a leading worldwide cause of disability, and there are
currently no medicines that prevent, reduce, or reverse acute or chronic neurodegeneration …

Exogenous interleukin 33 enhances the brain's lymphatic drainage and toxic protein clearance in acute traumatic brain injury mice

M Liu, J Huang, T Liu, J Yuan, C Lv, Z Sha… - Acta Neuropathologica …, 2023 - Springer
The persistent dysregulation and accumulation of poisonous proteins from destructive
neural tissues and cells activate pathological mechanisms after traumatic brain injury (TBI) …