Bioactivity assessment and toxicity of crocin: a comprehensive review
SH Alavizadeh, H Hosseinzadeh - Food and chemical toxicology, 2014 - Elsevier
Since ancient times, saffron, the dried stigma of the plant Crocus sativus L. has been
extensively used as a spice and food colorant; in folk medicine it has been reputed to be …
extensively used as a spice and food colorant; in folk medicine it has been reputed to be …
Saffron: a natural product with potential pharmaceutical applications
E Christodoulou, NPE Kadoglou… - Journal of Pharmacy …, 2015 - academic.oup.com
Objectives Recently, a great deal of interest has been developed to isolate and investigate
novel bioactive components from natural resources with health beneficial effects. Saffron is …
novel bioactive components from natural resources with health beneficial effects. Saffron is …
Protective effect of hesperidin on sodium arsenite-induced nephrotoxicity and hepatotoxicity in rats
The present study was conducted to investigate the protective effects of hesperidin (HSP)
against sodium arsenite (SA)-induced nephrotoxicity and hepatotoxicity in rats. Thirty-five …
against sodium arsenite (SA)-induced nephrotoxicity and hepatotoxicity in rats. Thirty-five …
[HTML][HTML] Protective effects of hesperidin on oxidative stress, dyslipidaemia and histological changes in iron-induced hepatic and renal toxicity in rats
L Pari, A Karthikeyan, P Karthika, A Rathinam - Toxicology reports, 2015 - Elsevier
The present study was to evaluate the protective role of hesperidin (HDN) against iron-
induced hepatic and renal toxicity in rats. Administration of iron (30 mg/kg body weight) …
induced hepatic and renal toxicity in rats. Administration of iron (30 mg/kg body weight) …
Evaluation of diazinon-induced hepatotoxicity and protective effects of crocin
P Lari, K Abnous, M Imenshahidi… - Toxicology and …, 2015 - journals.sagepub.com
Diazinon (DZN) is one of the most widely used insecticides in agricultural pest control.
Previous studies have shown that DZN may induce hepatotoxicity. Reactive oxygen species …
Previous studies have shown that DZN may induce hepatotoxicity. Reactive oxygen species …
An updated review on therapeutic effects of nanoparticle-based formulations of saffron components (safranal, crocin, and crocetin)
E Mirhadi, H Nassirli, B Malaekeh-Nikouei - Journal of Pharmaceutical …, 2020 - Springer
In recent years, nanotechnology has come to help researchers a lot in different fields.
Especially in medicine and drug delivery, it presents new methods and technologies to …
Especially in medicine and drug delivery, it presents new methods and technologies to …
Protective effect of crocin on liver toxicity induced by morphine
MR Salahshoor, S Roshankhah… - Research in …, 2016 - journals.lww.com
Crocin, a bioactive molecule of saffron can be purely isolated from the saffron extract. It has
different pharmacological effects such as antioxidant and anticancer activities. Morphine is …
different pharmacological effects such as antioxidant and anticancer activities. Morphine is …
ERK/NF-kB/COX-2 signaling pathway plays a key role in curcumin protection against acetaminophen-induced liver injury
AH Chou, HC Lee, CC Liao, HP Yu, FC Liu - Life, 2023 - mdpi.com
Recent experimental studies have highlighted the beneficial effects of curcumin on liver
injury induced by acetaminophen (APAP). However, the specific molecular mechanisms …
injury induced by acetaminophen (APAP). However, the specific molecular mechanisms …
[HTML][HTML] Curcumin improves liver damage in male mice exposed to nicotine
M Salahshoor, S Mohamadian, S Kakabaraei… - Journal of traditional and …, 2016 - Elsevier
The color of turmeric (薑黃 jiāng huáng) is because of a substance called curcumin. It has
different pharmacological effects, such as antioxidant and anti-inflammatory properties …
different pharmacological effects, such as antioxidant and anti-inflammatory properties …
Crocin protects the liver and kidney from patulin-induced apoptosis in vivo
M Boussabbeh, I Ben Salem, F Belguesmi… - … Science and Pollution …, 2016 - Springer
Patulin (PAT) is a mycotoxin mainly produced by Aspergillus, Penicillium, and Bissochlamys.
Given the high risk associated with this mycotoxin, its potential effects have been …
Given the high risk associated with this mycotoxin, its potential effects have been …