Increasing incidence of early-onset colorectal cancer

FA Sinicrope - New England Journal of Medicine, 2022 - Mass Medical Soc
Early-Onset Colorectal Cancer Early-onset disease (at< 50 years of age) accounts for 10%
of colorectal cancer cases, and the incidence is increasing, particularly in high-income …

Young-onset colorectal cancer

MCW Spaander, AG Zauber, S Syngal… - Nature reviews Disease …, 2023 - nature.com
In the past decades the incidence of colorectal cancer (CRC) in people under the age of 50
years has increased, which is referred to as early-onset CRC or young-onset CRC (YO …

Is early-onset cancer an emerging global epidemic? Current evidence and future implications

T Ugai, N Sasamoto, HY Lee, M Ando… - Nature Reviews …, 2022 - nature.com
Over the past several decades, the incidence of early-onset cancers, often defined as
cancers diagnosed in adults< 50 years of age, in the breast, colorectum, endometrium …

Updates on age to start and stop colorectal cancer screening: recommendations from the US Multi-Society Task Force on Colorectal Cancer

SG Patel, FP May, JC Anderson, CA Burke… - Gastroenterology, 2022 - Elsevier
This document is a focused update to the 2017 colorectal cancer (CRC) screening
recommendations from the US Multi-Society Task Force on Colorectal Cancer, which …

Dysbiosis of human gut microbiome in young-onset colorectal cancer

Y Yang, L Du, D Shi, C Kong, J Liu, G Liu, X Li… - Nature …, 2021 - nature.com
The incidence of sporadic young-onset colorectal cancer (yCRC) is increasing. A significant
knowledge gap exists in the gut microbiota and its diagnostic value for yCRC patients …

Risk factors for early-onset colorectal cancer: a systematic review and meta-analysis

DE O'Sullivan, RL Sutherland, S Town, K Chow… - Clinical …, 2022 - Elsevier
Background & Aims Despite the widespread increase in the incidence of early-onset
colorectal cancer (EoCRC), the reasons for this increase remain unclear. The objective of …

Rising incidence of early-onset colorectal cancer—A call to action

N Akimoto, T Ugai, R Zhong, T Hamada… - Nature reviews Clinical …, 2021 - nature.com
The incidence of early-onset colorectal cancer (CRC), which occurs in individuals< 50 years
of age, has been increasing worldwide and particularly in high-income countries. The …

[HTML][HTML] Integrated omics of metastatic colorectal cancer

C Li, YD Sun, GY Yu, JR Cui, Z Lou, H Zhang, Y Huang… - Cancer cell, 2020 - cell.com
We integrate the genomics, proteomics, and phosphoproteomics of 480 clinical tissues from
146 patients in a Chinese colorectal cancer (CRC) cohort, among which 70 had metastatic …

Epidemiology and mechanisms of the increasing incidence of colon and rectal cancers in young adults

EM Stoffel, CC Murphy - Gastroenterology, 2020 - Elsevier
In contrast to the decreasing incidence of colorectal cancer (CRC) in older populations, the
incidence has nearly doubled in younger adults since the early 1990s. Approximately 1 in …

The rising tide of early-onset colorectal cancer: a comprehensive review of epidemiology, clinical features, biology, risk factors, prevention, and early detection

SG Patel, JJ Karlitz, T Yen, CH Lieu… - The lancet …, 2022 - thelancet.com
The incidence of early-onset colorectal—ie, colorectal cancer cancer diagnosed in patients
under the age of 50 years—has been increasing around the world. This Series paper …