Electronic health records (EHRs) are a rich source of data for researchers, but extracting
meaningful information out of this highly complex data source is challenging. Phecodes …

Drugs whose targets have genetic evidence to support efficacy and safety are more likely to
be approved after clinical development. In this paper, we provide an overview of how natural …

OBJECTIVE COVID-19 has become a major public health problem. There is good evidence
that ACE2 is a receptor for SARS-CoV-2, and high expression of ACE2 may increase …

Tremendous progress has been made with continually expanding genomics technologies to
unravel and understand crop genomes. However, the impact of genomics data on crop …

Genome-wide association studies have identified many variants that each affects multiple
traits, particularly across autoimmune diseases, cancers and neuropsychiatric disorders …

In drug discovery, network‐based approaches are expected to spotlight our understanding
of drug action across multiple layers of information. On one hand, network pharmacology …

Background Evaluation and interpretation of the literature on obstructive sleep apnea (OSA)
allows for consolidation and determination of the key factors important for clinical …

Advances in genotyping technology have, over the past decade, enabled the focused
search for common genetic variation associated with human diseases and traits. With the …

The genome-wide association study (GWAS) approach has discovered hundreds of genetic
variants associated with diseases and quantitative traits. However, despite clinical overlap …

The last decade has seen an exponential growth in the quantity of clinical data collected
nationwide, triggering an increase in opportunities to reuse the data for biomedical research …