Hidradenitis suppurativa: epidemiology, clinical presentation, and pathogenesis
SR Goldburg, BE Strober, MJ Payette - Journal of the American Academy …, 2020 - Elsevier
Hidradenitis suppurativa (HS) is an inflammatory disorder that is characterized by chronic
deep-seated nodules, abscesses, fistulae, sinus tracts, and scars in the axilla, inguinal area …
deep-seated nodules, abscesses, fistulae, sinus tracts, and scars in the axilla, inguinal area …
Pathophysiology of hidradenitis suppurativa: an update
E Prens, I Deckers - Journal of the American Academy of Dermatology, 2015 - Elsevier
The pathogenesis of hidradenitis suppurativa (HS) or acne inversa is not completely
understood. Recent research has led to greater insight into the mechanisms involved in the …
understood. Recent research has led to greater insight into the mechanisms involved in the …
Dysregulated cytokine expression in lesional and nonlesional skin in hidradenitis suppurativa
G Kelly, R Hughes, T McGarry… - British Journal of …, 2015 - academic.oup.com
Background There is a dearth of information on the precise pathogenesis of hidradenitis
suppurativa (HS), but immune dysregulation is implicated. Objectives To determine the …
suppurativa (HS), but immune dysregulation is implicated. Objectives To determine the …
Epigenetic switch reshapes epithelial progenitor cell signatures and drives inflammatory pathogenesis in hidradenitis suppurativa
Hidradenitis suppurativa (HS) is a complex inflammatory skin disease with undefined
mechanistic underpinnings. Here, we investigated HS epithelial cells and demonstrated that …
mechanistic underpinnings. Here, we investigated HS epithelial cells and demonstrated that …
Paradoxical reactions under TNF-α blocking agents and other biological agents given for chronic immune-mediated diseases: an analytical and comprehensive …
É Toussirot, F Aubin - RMD open, 2016 - rmdopen.bmj.com
Paradoxical adverse events (PAEs) have been reported during biological treatment for
chronic immune-mediated diseases. PAEs are defined as the occurrence during biological …
chronic immune-mediated diseases. PAEs are defined as the occurrence during biological …
Increased interleukin (IL)-17 serum levels in patients with hidradenitis suppurativa: Implications for treatment with anti-IL-17 agents
Ł Matusiak, J Szczęch, A Bieniek… - Journal of the American …, 2017 - Elsevier
Background Biologics seem to offer a promising nonsurgical approach in hidradenitis
suppurativa (HS), especially in disease with highly pronounced inflammation. Recent …
suppurativa (HS), especially in disease with highly pronounced inflammation. Recent …
[HTML][HTML] Hidradenitis suppurativa: causes, features, and current treatments
C Vinkel, SF Thomsen - The Journal of clinical and aesthetic …, 2018 - ncbi.nlm.nih.gov
Hidradenitis suppurativa (HS), a relatively common and chronic inflammatory skin disorder.
HS can have debilitating consequences if not diagnosed and treated appropriately …
HS can have debilitating consequences if not diagnosed and treated appropriately …
[HTML][HTML] MABp1 targeting IL-1α for moderate to severe hidradenitis suppurativa not eligible for adalimumab: a randomized study
T Kanni, M Argyropoulou, T Spyridopoulos… - Journal of Investigative …, 2018 - Elsevier
Patients with moderate to severe hidradenitis suppurativa failing adalimumab therapy, or
those ineligible to receive it, remain a population with an unmet need. Twenty patients not …
those ineligible to receive it, remain a population with an unmet need. Twenty patients not …
[HTML][HTML] Cytokine pathways and investigational target therapies in hidradenitis suppurativa
E Del Duca, P Morelli, L Bennardo… - International journal of …, 2020 - mdpi.com
Background: Hidradenitis suppurativa (HS) is a chronic inflammatory skin disease affecting
areas with a high density of apocrine glands and characterized by subcutaneous nodules …
areas with a high density of apocrine glands and characterized by subcutaneous nodules …
The clinical significance of increased serum proinflammatory cytokines, C‐reactive protein, and erythrocyte sedimentation rate in patients with hidradenitis suppurativa
D Jiménez-Gallo… - Mediators of …, 2017 - Wiley Online Library
Objectives. To assess inflammatory serum markers including serum proinflammatory
cytokines, C‐reactive protein (CRP), and erythrocyte sedimentation rate (ESR) according to …
cytokines, C‐reactive protein (CRP), and erythrocyte sedimentation rate (ESR) according to …