Long noncoding RNA (lncRNA)-mediated competing endogenous RNA networks provide novel potential biomarkers and therapeutic targets for colorectal cancer

L Wang, KB Cho, Y Li, G Tao, Z Xie, B Guo - International journal of …, 2019 - mdpi.com
Colorectal cancer (CRC) is the third most common cancer and has a high metastasis and
reoccurrence rate. Long noncoding RNAs (lncRNAs) play an important role in CRC growth …

Biomarkers in colorectal cancer: current research and future prospects

OO Ogunwobi, F Mahmood, A Akingboye - International journal of …, 2020 - mdpi.com
Colorectal cancer (CRC) is a leading cause of death worldwide, despite progress made in
detection and management through surgery, chemotherapy, radiotherapy, and …

LncRNA–FEZF1-AS1 promotes tumor proliferation and metastasis in colorectal cancer by regulating PKM2 signaling

Z Bian, J Zhang, M Li, Y Feng, X Wang, J Zhang… - Clinical Cancer …, 2018 - AACR
Abstract Purpose: Long non-coding RNAs (lncRNAs) play key roles in human cancers. Here,
FEZF1-AS1, a highly overexpressed lncRNA in colorectal cancer, was identified by lncRNA …

[HTML][HTML] LncRNA—UCA1 enhances cell proliferation and 5-fluorouracil resistance in colorectal cancer by inhibiting miR-204-5p

Z Bian, L Jin, J Zhang, Y Yin, C Quan, Y Hu, Y Feng… - Scientific reports, 2016 - nature.com
Recent preliminary studies reported the in vitro tumor-promoting effects of long non-coding
RNA urothelial carcinoma associated 1 (UCA1) in colorectal cancer (CRC). However, the in …

The immune-microenvironment confers chemoresistance of colorectal cancer through macrophage-derived IL6

Y Yin, S Yao, Y Hu, Y Feng, M Li, Z Bian, J Zhang… - Clinical Cancer …, 2017 - AACR
Abstract Purpose: Tumor-associated macrophages (TAMs) are frequently associated with
poor prognosis in human cancers. However, the effects of TAMs in colorectal cancer are …

Long noncoding RNA LINC01234 functions as a competing endogenous RNA to regulate CBFB expression by sponging miR-204-5p in gastric cancer

X Chen, Z Chen, S Yu, F Nie, S Yan, P Ma, Q Chen… - Clinical Cancer …, 2018 - AACR
Abstract Purpose: Long noncoding RNAs (lncRNAs) have emerged as important regulators
in a variety of human diseases, including cancers. However, the overall biological roles and …

MiR-26 enhances chemosensitivity and promotes apoptosis of hepatocellular carcinoma cells through inhibiting autophagy

F Jin, Y Wang, M Li, Y Zhu, H Liang, C Wang… - Cell death & …, 2018 - nature.com
Hepatocellular carcinoma (HCC) generally possesses a high resistance to chemotherapy.
Given that autophagy is an important factor promoting tumor chemoresistance and HCC …

Tumor suppressor miRNA-204-5p regulates growth, metastasis, and immune microenvironment remodeling in breast cancer

BS Hong, HS Ryu, N Kim, J Kim, E Lee, H Moon… - Cancer research, 2019 - AACR
Various miRNAs play critical roles in the development and progression of solid tumors. In
this study, we describe the role of miR-204-5p in limiting growth and progression of breast …

[HTML][HTML] The c-Myc/miR-27b-3p/ATG10 regulatory axis regulates chemoresistance in colorectal cancer

W Sun, J Li, L Zhou, J Han, R Liu, H Zhang, T Ning… - Theranostics, 2020 - ncbi.nlm.nih.gov
Oxaliplatin (OXA) resistance is the major obstacle to the anticancer effects of chemotherapy
in colorectal cancer (CRC) patients. MicroRNAs (miRNAs) play an important role in the …

miR-29c-3p inhibits autophagy and cisplatin resistance in ovarian cancer by regulating FOXP1/ATG14 pathway

Z Hu, M Cai, Y Zhang, L Tao, R Guo - Cell Cycle, 2020 - Taylor & Francis
Autophagy, characterized by the elevator of autophagy-related gene 14 (ATG14) and the
dysregulation of autophagy-related proteins, contributes to the cisplatin (DDP) resistance in …