Antibodies play an essential role in host defence against pathogens by recognizing
microorganisms or infected cells. Although preventing pathogen entry is one potential …

The transmission of dengue virus (DENV) from an infected Aedes mosquito to a human,
causes illness ranging from mild dengue fever to fatal dengue shock syndrome. The similar …

Antiviral activities of antibodies may either be dependent only on interactions between the
antibody and cognate antigen, as in binding and neutralization of an infectious virion, or …

Dengue is a mosquito-borne viral disease (arboviral) caused by the Dengue virus. It is one
of the prominent public health problems in tropical and subtropical regions with no effective …

IgG3 comprises only a minor fraction of IgG and has remained relatively understudied until
recent years. Key physiochemical characteristics of IgG3 include an elongated hinge region …

Dengue fever is an Aedes mosquito-borne illness caused by any one of the four different
dengue virus (DENV) serotypes (1–4) and manifests in the form of symptoms ranging from …

Antiviral antibodies constitute an important component of the host immune response against
viral infections and serve to neutralize and reduce infectivity of the virus. However, these …

The dogma is that the human immune system protects us against pathogens. Yet, several
viruses, like dengue virus, antagonize the hosts' antibodies to enhance their viral load and …

Antibody-dependent enhancement (ADE) is a phenomenon in which preexisting poorly
neutralizing antibodies leads to enhanced infection. It is a serious concern with mosquito …

Zika virus (ZIKV) has been known for decades to circulate in Africa and Asia. However,
major complications of a ZIKV infection have recently become apparent for reasons that are …