Progress towards biocompatible intracortical microelectrodes for neural interfacing applications

M Jorfi, JL Skousen, C Weder… - Journal of neural …, 2014 - iopscience.iop.org
To ensure long-term consistent neural recordings, next-generation intracortical
microelectrodes are being developed with an increased emphasis on reducing the neuro …

[HTML][HTML] Tissue response to neural implants: the use of model systems toward new design solutions of implantable microelectrodes

M Gulino, D Kim, S Pané, SD Santos… - Frontiers in …, 2019 - frontiersin.org
The development of implantable neuroelectrodes is advancing rapidly as these tools are
becoming increasingly ubiquitous in clinical practice, especially for the treatment of …

Nanotopography-enhanced biomimetic coating maintains bioactivity after weeks of dry storage and improves chronic neural recording

K Woeppel, V Dhawan, D Shi, XT Cui - Biomaterials, 2023 - Elsevier
We developed a nanoparticle base layer technology capable of maintaining the bioactivity of
protein-based neural probe coating intended to improve neural recording quality. When …

[HTML][HTML] 3D-nanostructured boron-doped diamond for microelectrode array neural interfacing

G Piret, C Hébert, JP Mazellier, L Rousseau… - Biomaterials, 2015 - Elsevier
The electrode material is a key element in the design of long-term neural implants and
neuroprostheses. To date, the ideal electrode material offering high longevity …

Biological responses to immobilized microscale and nanoscale surface topographies

SA Skoog, G Kumar, RJ Narayan, PL Goering - Pharmacology & …, 2018 - Elsevier
Cellular responses are highly influenced by biochemical and biomechanical interactions
with the extracellular matrix (ECM). Due to the impact of ECM architecture on cellular …

[HTML][HTML] Peripheral nerve bionic interface: a review of electrodes

C Russell, AD Roche, S Chakrabarty - International Journal of Intelligent …, 2019 - Springer
As the demand for sensory feedback to and from prosthetic limbs becomes increasingly
desirable, implantable neural interfaces are becoming more attractive. Here, we briefly …

Nanoparticle and biomolecule surface modification synergistically increases neural electrode recording yield and minimizes inflammatory host response

KM Woeppel, XT Cui - Advanced healthcare materials, 2021 - Wiley Online Library
Due to their ability to interface with neural tissues, neural electrodes are the key tool used for
neurophysiological studies, electrochemical detection, brain computer interfacing, and …

Effects of neuronal cell adhesion molecule L1 and nanoparticle surface modification on microglia

N Kushwah, K Woeppel, V Dhawan, D Shi, XT Cui - Acta biomaterialia, 2022 - Elsevier
Microelectrode arrays for neural recording suffer from low yield and stability partly due to the
inflammatory host responses. A neuronal cell adhesion molecule L1 coating has been …

Enhanced GLT-1 mediated glutamate uptake and migration of primary astrocytes directed by fibronectin-coated electrospun poly-l-lactic acid fibers

JM Zuidema, MC Hyzinski-García, K Van Vlasselaer… - Biomaterials, 2014 - Elsevier
Bioengineered fiber substrates are increasingly studied as a means to promote regeneration
and remodeling in the injured central nervous system (CNS). Previous reports largely …

Nanoporous gold biointerfaces: modifying nanostructure to control neural cell coverage and enhance electrophysiological recording performance

CAR Chapman, L Wang, H Chen… - Advanced functional …, 2017 - Wiley Online Library
Nanostructured neural interface coatings have significantly enhanced recording fidelity in
both implantable and in vitro devices. As such, nanoporous gold (np‐Au) has shown …