Thousands of new experimental datasets are becoming available every day; in many cases,
they are produced within the scope of large cooperative efforts, involving a variety of …

With the availability of reliable and low-cost DNA sequencing, human genomics is relevant
to a growing number of end-users, including biologists and clinicians. Typical interactions …

Abstract The Gene Expression Omnibus (GEO) is a public archive containing> 4 million
digital samples from functional genomics experiments collected over almost two decades …

Genomic data are growing at unprecedented pace, along with new protocols, update
polices, formats and guidelines, terminologies and ontologies, which are made available …

Background Precision medicine is a promising approach that has revolutionized disease
prevention and individualized treatment. The DELFOS oracle is a model-driven genomics …

The human genome is traditionally represented as a DNA sequence of three billion base
pairs. However, its intricacies are captured by many more complex signals, representing …

The human genome complexity is captured by many signals, representing for instance DNA
variations, the expression of gene activity, or DNA's structural rearrangements; a rich set of …

NoSQL database can provide massive, high concurrency, and scalable services for storing
different types of data. HBase, a type of NoSQL database, in which columns are grouped …

Background All aspects of our society, including the life sciences, need a mechanism for
people working within them to represent the concepts they employ to carry out their …

Abstract Background Genome Wide Association Studies (GWAS) are based on the
observation of genome-wide sets of genetic variants–typically single-nucleotide …