Selenium biochemistry and its role for human health

M Roman, P Jitaru, C Barbante - Metallomics, 2014 - academic.oup.com
Despite its very low level in humans, selenium plays an important and unique role among
the (semi) metal trace essential elements because it is the only one for which incorporation …

Selenium as a bioactive micronutrient in the human diet and its cancer chemopreventive activity

D Radomska, R Czarnomysy, D Radomski… - Nutrients, 2021 - mdpi.com
This review answers the question of why selenium is such an important trace element in the
human diet. Daily dietary intake of selenium and its content in various food products is …

Which form is that? The importance of selenium speciation and metabolism in the prevention and treatment of disease

CM Weekley, HH Harris - Chemical Society Reviews, 2013 - pubs.rsc.org
The biological activity of selenium is dependent upon its speciation. We aim to integrate
selenium speciation and metabolism into a discussion of the mechanisms by which …

Vitamin and mineral supplements in the primary prevention of cardiovascular disease and cancer: an updated systematic evidence review for the US Preventive …

SP Fortmann, BU Burda, CA Senger, JS Lin… - Annals of internal …, 2013 - acpjournals.org
Background: Vitamin and mineral supplements are commonly used to prevent chronic
diseases. Purpose: To systematically review evidence for the benefit and harms of vitamin …

Theranostic applications of selenium nanomedicines against lung cancer

S Liu, W Wei, J Wang, T Chen - Journal of Nanobiotechnology, 2023 - Springer
The incidence and mortality rates of lung cancer are among the highest in the world.
Traditional treatment methods include surgery, chemotherapy, and radiotherapy. Although …

Selenium, selenoproteins and cancer of the thyroid

RM Rua, F Nogales, O Carreras, ML Ojeda - Journal of Trace Elements in …, 2023 - Elsevier
Selenium is an essential mineral element with important biological functions for the whole
body through incorporation into selenoproteins. This element is highly concentrated in the …

Zinc and selenium in inflammatory bowel disease: trace elements with key roles?

M Vaghari-Tabari, D Jafari-Gharabaghlou… - … Trace Element Research, 2021 - Springer
Inflammatory bowel disease (IBD) is a chronic inflammatory condition that may emerge at a
young age and often lasts for life. It often goes through phases of recurrence and remission …

Drugs for preventing lung cancer in healthy people

M Cortés‐Jofré, JR Rueda… - Cochrane Database …, 2020 - cochranelibrary.com
Background This is the second update of this Cochrane Review. Some studies have
suggested a protective effect of antioxidant nutrients and higher dietary levels of fruits and …

Strategies for the development of selenium-based anticancer drugs

P Collery - Journal of Trace Elements in Medicine and Biology, 2018 - Elsevier
Many experimental models demonstrated that inorganic and organic selenium (Se)
compounds may have an anticancer activity. However, large clinical studies failed to …

Selenium inhibits Staphylococcus aureus-induced inflammation by suppressing the activation of the NF-κB and MAPK signalling pathways in RAW264. 7 …

CL Bi, H Wang, YJ Wang, J Sun, JS Dong… - European journal of …, 2016 - Elsevier
Inflammation is the hallmark of Staphylococcus aureus (S. aureus)-induced mastitis. Given
the interesting relationship between selenium levels and inflammation, this study aimed to …